{"id":"W2795445414","doi":"10.1200/jco.2018.36.4_suppl.723","title":"KEYNOTE-059 cohort 1: Pembrolizumab (Pembro) monotherapy in previously treated advanced gastric or gastroesophageal junction (G/GEJ) cancer in patients (Pts) with PD-L1+ tumors—Asian subgroup analysis.","year":2018,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Gastric Cancer Management and Outcomes","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre","funders":"","keywords":"Medicine; Pembrolizumab; Cohort; Internal medicine; Cancer; Oncology; Adenocarcinoma; Microsatellite instability; Gastroenterology; Immunotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00161066,0.001190634,0.001254182,0.0005640427,0.0004691969,0.001049507,0.00083837,0.0007931186,0.004235163],"category_scores_gemma":[0.001265123,0.0004936123,0.003814358,0.0008270473,0.0003750376,0.0006763084,0.0007852588,0.001094445,0.0006753426],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00100315,"about_ca_system_score_gemma":0.001883294,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002776464,"about_ca_topic_score_gemma":0.008295105,"domain_scores_codex":[0.9993157,0.0001818819,0.00009001412,0.00020946,0.00008869603,0.0001140607],"domain_scores_gemma":[0.999216,0.00008489953,0.0002618278,0.0001587214,0.00008425899,0.0001943644],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"observational","study_design_scores_codex":[0.6208202,0.006320277,0.2827373,0.00169052,0.0282519,0.0008913499,0.0004718999,0.001990499,0.01880047,0.0003050382,0.01047988,0.02724068],"study_design_scores_gemma":[0.1915597,0.09562663,0.6331283,0.00038042,0.04269836,0.003120558,0.001240151,0.003848136,0.00738273,0.0007399023,0.0200349,0.0002401431],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9833318,0.001844864,0.0003883281,0.0001789033,0.0000657044,0.001330019,0.01165166,0.00003337743,0.001175287],"genre_scores_gemma":[0.9763703,0.0006966761,0.0008471415,0.0004635282,0.0001081572,0.00130373,0.0187976,0.00003093802,0.001381869],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004235163,"threshold_uncertainty_score":0.01416808,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03521878479211881,"score_gpt":0.3942529768204152,"score_spread":0.3590341920282964,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}