{"id":"W2795926106","doi":"10.1002/jhet.3153","title":"Phosphotungstic Acid Catalyzed One Pot Synthesis of 4,8,8‐Trimethyl‐5‐phenyl‐5,5a,8,9‐tetrahydrobenzo[b] [1,8]Naphthyridin‐6(7H)‐one Derivatives and Their Biological Evaluation Against A549 Lung Cancer Cells","year":2018,"lang":"en","type":"article","venue":"Journal of Heterocyclic Chemistry","topic":"Synthesis and biological activity","field":"Chemistry","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Winnipeg","funders":"Durban University of Technology","keywords":"Chemistry; Phosphotungstic acid; Catalysis; Benzaldehyde; Cyclohexane; Viability assay; Solvent; One-pot synthesis; A549 cell; Organic chemistry; Combinatorial chemistry; Nuclear chemistry; Cell; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008576937,0.0003669577,0.000226457,0.0002340037,0.0001143185,0.00009506798,0.0002774611,0.0002194299,0.001256987],"category_scores_gemma":[0.00006007342,0.0001720476,0.0001583959,0.0002176733,0.00009506481,0.000228579,0.0001369917,0.0002471242,0.0004228111],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001589286,"about_ca_system_score_gemma":0.0002622778,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004266654,"about_ca_topic_score_gemma":0.001422216,"domain_scores_codex":[0.999953,0.000005106584,0.000005470776,0.00001121562,0.00001278888,0.00001244012],"domain_scores_gemma":[0.999969,0.000003436093,0.000009955019,0.000003835455,0.000005736413,0.000007935736],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003578477,0.00004043037,0.0000497442,0.0001262194,0.000006326467,0.000102076,0.00002067265,0.000267583,0.9940795,0.0001512124,0.0000745564,0.005046043],"study_design_scores_gemma":[0.00001617073,0.0005842679,0.0008918487,0.000005861036,0.00001500998,0.0002606026,0.00001387747,0.0006589578,0.9944536,0.00005405342,0.003036337,0.00000935591],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9625085,0.004411501,0.02159216,0.0001455012,0.00008868954,0.0002515497,0.001061748,0.0002971706,0.009643206],"genre_scores_gemma":[0.9770418,0.002746328,0.01363637,0.00004180324,0.00001405491,0.00009792449,0.0004903413,0.00002619435,0.005905177],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001256987,"threshold_uncertainty_score":0.004204988,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0343211599578205,"score_gpt":0.2742309227541356,"score_spread":0.2399097627963151,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}