{"id":"W2795926106","doi":"10.1002/jhet.3153","title":"Phosphotungstic Acid Catalyzed One Pot Synthesis of 4,8,8‐Trimethyl‐5‐phenyl‐5,5a,8,9‐tetrahydrobenzo[b] [1,8]Naphthyridin‐6(7H)‐one Derivatives and Their Biological Evaluation Against A549 Lung Cancer Cells","year":2018,"lang":"en","type":"article","venue":"Journal of Heterocyclic Chemistry","topic":"Synthesis and biological activity","field":"Chemistry","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Winnipeg","funders":"Durban University of Technology","keywords":"Chemistry; Phosphotungstic acid; Catalysis; Benzaldehyde; Cyclohexane; Viability assay; Solvent; One-pot synthesis; A549 cell; Organic chemistry; Combinatorial chemistry; Nuclear chemistry; Cell; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0007828685,0.0004914665,0.001180246,0.00006714949,0.000176245,0.00005512285,0.0005488112,0.0005201902,0.001723907],"category_scores_gemma":[0.001565375,0.0003420953,0.0004156808,0.0002051159,0.0006441869,0.0001927525,0.0001955711,0.0005367283,0.000002731112],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002669703,"about_ca_system_score_gemma":0.00009587147,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003617838,"about_ca_topic_score_gemma":0.000003294848,"domain_scores_codex":[0.9970906,0.0001400421,0.001141919,0.00055605,0.0005754326,0.0004959713],"domain_scores_gemma":[0.9960119,0.001006836,0.001794416,0.000421709,0.0004755543,0.0002895957],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004483826,0.0006331194,0.003277111,0.0002981777,0.000544667,0.000005225705,0.0001570984,0.000005809008,0.9705746,4.647331e-7,0.0000525483,0.02400276],"study_design_scores_gemma":[0.0009145559,0.00007908732,0.003679382,0.0006361966,0.000264775,0.00004082584,0.000225568,0.0004147322,0.9931226,0.0001198258,0.00009997651,0.0004024268],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.993954,0.004066586,0.0001396644,0.0001693593,0.0001138357,0.0001257059,0.0001232417,0.00003056993,0.001277043],"genre_scores_gemma":[0.9970019,0.001644755,0.000518705,0.00005050328,0.000683678,0.00002913501,0.00001288117,0.00003206417,0.00002633046],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02360033,"threshold_uncertainty_score":0.9999031,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0343211599578205,"score_gpt":0.2742309227541356,"score_spread":0.2399097627963151,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}