{"id":"W2795941895","doi":"10.3389/fonc.2018.00093","title":"Development of Neuroendocrine Prostate Cancers by the Ser/Arg Repetitive Matrix 4-Mediated RNA Splicing Network","year":2018,"lang":"en","type":"article","venue":"Frontiers in Oncology","topic":"Prostate Cancer Treatment and Research","field":"Medicine","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Canadian Institutes of Health Research","keywords":"Prostate cancer; RNA splicing; Androgen receptor; Cancer research; Reprogramming; Alternative splicing; Biology; Transcriptome; Cancer; RNA; Gene; Exon; Gene expression; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003425076,0.0001611581,0.0004399545,0.0001183408,0.0001326541,0.000005995324,0.0001560683,0.00006208802,0.00007165129],"category_scores_gemma":[0.00008235476,0.0001084887,0.00004372038,0.0004966541,0.00047342,0.00004136924,0.00009890844,0.0003082122,0.00001301298],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001153675,"about_ca_system_score_gemma":0.00112784,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001740472,"about_ca_topic_score_gemma":0.0002755999,"domain_scores_codex":[0.9983265,0.0001238722,0.0004150575,0.0003116394,0.0002359871,0.0005869427],"domain_scores_gemma":[0.9992594,0.00009663786,0.0001605719,0.0002326547,0.0001385794,0.0001121427],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.009709232,0.0004664325,0.1979003,0.0002389129,0.000799878,0.0009226695,0.01023916,0.0001070443,0.01162848,0.00008240643,0.5442548,0.2236507],"study_design_scores_gemma":[0.0113707,0.003220085,0.02154097,0.0003569709,0.0001267666,0.0001265542,0.004090994,0.001858596,0.0449607,0.0002844006,0.9117098,0.0003534862],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9786134,0.004608545,0.0008557837,0.004904693,0.002049849,0.001748366,0.00003269624,0.00005537708,0.007131234],"genre_scores_gemma":[0.9557865,0.003488004,0.02704774,0.001442796,0.0006974909,0.0004076301,0.0002156199,0.00007632511,0.0108379],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3674549,"threshold_uncertainty_score":0.4424039,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01562578038948693,"score_gpt":0.3302936314034954,"score_spread":0.3146678510140085,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}