{"id":"W2796092158","doi":"10.1016/j.molcel.2018.03.001","title":"Odilorhabdins, Antibacterial Agents that Cause Miscoding by Binding at a New Ribosomal Site","year":2018,"lang":"en","type":"article","venue":"Molecular Cell","topic":"Antibiotic Resistance in Bacteria","field":"Biochemistry, Genetics and Molecular Biology","cited_by":139,"is_retracted":false,"has_abstract":false,"ca_institutions":"Micropharma (Canada)","funders":"Argonne National Laboratory; Nuclear Physics; Direction Générale de l’Armement; Office of Science; Illinois State University; National Institutes of Health; National Center for Research Resources; National Institute of General Medical Sciences; European Federation of Pharmaceutical Industries and Associations","keywords":"Biology; Binding site; Ribosomal protein; Computational biology; Ribosome; Biochemistry; RNA","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002017251,0.0004694714,0.0003842576,0.0002308947,0.0002912773,0.0003006668,0.0003092899,0.0003842769,0.0007939851],"category_scores_gemma":[0.0002313229,0.0001649456,0.0002437657,0.0001370702,0.0004359141,0.0002301062,0.0003290887,0.0006912141,0.0004185891],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005026394,"about_ca_system_score_gemma":0.0003429533,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009752305,"about_ca_topic_score_gemma":0.001764932,"domain_scores_codex":[0.9997513,0.00003167012,0.00001963309,0.00005519907,0.00008310151,0.00005906711],"domain_scores_gemma":[0.9996225,0.00007316894,0.0001410744,0.00005281538,0.00004045342,0.00007002641],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001259242,0.00001408298,0.0002182664,0.00002943454,0.000003087355,0.00007200197,0.00001287965,0.00004280993,0.9973717,0.0002303496,0.00005125516,0.001828273],"study_design_scores_gemma":[0.000009016921,0.0001713473,0.001650127,0.000004837202,0.00000952999,0.0002117369,0.00003299477,0.0001534009,0.9943975,0.00007869369,0.003275949,0.000004941511],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9852602,0.003074038,0.005424067,0.0002468153,0.00009684857,0.00006528326,0.0003702173,0.0003129407,0.005149543],"genre_scores_gemma":[0.9925781,0.000794624,0.003976293,0.0001202848,0.00001395355,0.00002273203,0.0003500216,0.00004610144,0.002097946],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009752305,"threshold_uncertainty_score":0.00364697,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01455220058229645,"score_gpt":0.2461030539595282,"score_spread":0.2315508533772317,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}