{"id":"W2796115040","doi":"10.1182/blood.v130.suppl_1.741.741","title":"Deep and Durable Responses in Patients (Pts) with Relapsed/Refractory Multiple Myeloma (MM) Treated with Monotherapy GSK2857916, an Antibody Drug Conjugate Against B-Cell Maturation Antigen (BCMA): Preliminary Results from Part 2 of Study BMA117159","year":2017,"lang":"en","type":"article","venue":"Blood","topic":"Multiple Myeloma Research and Treatments","field":"Medicine","cited_by":38,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; BC Cancer Agency; University of Toronto","funders":"","keywords":"Medicine; Multiple myeloma; Antibody; Internal medicine; Plasma cell leukemia; Pharmacokinetics; Immunology; Pharmacology; Oncology; Gastroenterology; Cancer research","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007956556,0.0005990641,0.001491301,0.0003153852,0.0002314025,0.0004294868,0.0002779419,0.0004634044,0.001656759],"category_scores_gemma":[0.0005091361,0.0002197886,0.0009338426,0.0002913081,0.0002663123,0.0003375167,0.0002557191,0.00120749,0.0003935694],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005449285,"about_ca_system_score_gemma":0.000510903,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007124695,"about_ca_topic_score_gemma":0.001535597,"domain_scores_codex":[0.9997285,0.0001094311,0.00002164395,0.00005071017,0.00003857429,0.00005107856],"domain_scores_gemma":[0.9996418,0.00007394184,0.00008099143,0.00002409977,0.0000200711,0.0001590984],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.3594783,0.03595047,0.1065688,0.001151766,0.002244476,0.001758958,0.0008271336,0.004484606,0.1852136,0.0001584651,0.003780476,0.298383],"study_design_scores_gemma":[0.05900584,0.6620143,0.2527743,0.00004601172,0.001451965,0.001625938,0.0001676394,0.001895265,0.01675632,0.0001277697,0.004097483,0.00003723585],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9972837,0.001126103,0.0001773618,0.00009417899,0.00001753641,0.0002656456,0.000425589,0.00002356588,0.0005862559],"genre_scores_gemma":[0.9961683,0.0008950354,0.0004308234,0.0002284997,0.00006176995,0.0002143995,0.001191375,0.0000106414,0.000799262],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001656759,"threshold_uncertainty_score":0.005542457,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01649827824944232,"score_gpt":0.2736216586074257,"score_spread":0.2571233803579834,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}