{"id":"W2796283437","doi":"10.1101/265355","title":"The DNA repair associated protein Gadd45 <i>γ</i> regulates the temporal coding of immediate early gene expression and is required for the consolidation of associative fear memory","year":2018,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Health and Medical Research Council; Natural Sciences and Engineering Research Council of Canada; University of Queensland; National Institutes of Health; Westpac Bicentennial Foundation","keywords":"Immediate early gene; Memory consolidation; DNA demethylation; DNA methylation; Biology; DNA repair; Epigenetics; Histone; Neuroscience; DNA damage; Gene expression; DNA; Gene; Genetics; Hippocampus","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007895969,0.0002029136,0.0001616996,0.0001489643,0.0001140946,0.0003705745,0.0001672568,0.0001422591,0.000760506],"category_scores_gemma":[0.0001129677,0.0001319514,0.000239953,0.00007733879,0.0002483525,0.000154158,0.0002331165,0.0004377755,0.0002594089],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000279747,"about_ca_system_score_gemma":0.0001459278,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006905789,"about_ca_topic_score_gemma":0.0006326516,"domain_scores_codex":[0.9999083,0.000008222254,0.000006503247,0.00002771824,0.00001899854,0.00003016837],"domain_scores_gemma":[0.9998884,0.000007082791,0.00004450241,0.00001216058,0.00001590291,0.00003202742],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006320565,0.000007377776,0.000527953,0.00001584329,0.000004037856,0.00003008312,0.00001082028,0.0000417462,0.9983985,0.0001107153,0.00002921941,0.0007605572],"study_design_scores_gemma":[0.00001674358,0.0001594588,0.03733296,0.00001431059,0.00001880835,0.0002680743,0.0000811629,0.001470434,0.9581714,0.0001998948,0.002259938,0.000006667392],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9894271,0.001672485,0.006599707,0.0001154302,0.00004342861,0.00001718188,0.0002429126,0.0001916266,0.001690128],"genre_scores_gemma":[0.9973666,0.0002847298,0.0008125635,0.00005176702,0.000004182742,0.000007356472,0.0001628967,0.00001651539,0.001293499],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000760506,"threshold_uncertainty_score":0.002544105,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01383320299311976,"score_gpt":0.2353102546082632,"score_spread":0.2214770516151435,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}