{"id":"W2796324723","doi":"10.1128/jvi.02241-17","title":"Visualization of Arenavirus RNA Species in Individual Cells by Single-Molecule Fluorescence <i>In Situ</i> Hybridization Suggests a Model of Cyclical Infection and Clearance during Persistence","year":2018,"lang":"en","type":"article","venue":"Journal of Virology","topic":"Viral Infections and Outbreaks Research","field":"Medicine","cited_by":24,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"National Institute of Allergy and Infectious Diseases; National Heart, Lung, and Blood Institute; Canadian Institutes of Health Research; National Center for Research Resources; National Institute of General Medical Sciences; Institut Pasteur; Fondation pour la Recherche Médicale; Government of Canada; National Institutes of Health; Agence Nationale de la Recherche","keywords":"Arenavirus; Biology; Virology; Transcription (linguistics); Viral replication; RNA; Lymphocytic choriomeningitis; Viral entry; Messenger RNA; Virus; Subgenomic mRNA; Molecular biology; Gene; Genetics; In vitro","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002029065,0.0002259455,0.0001680498,0.0003093197,0.0002608561,0.0003995295,0.0002928212,0.0004413192,0.001306421],"category_scores_gemma":[0.000167911,0.0002501124,0.000226399,0.0001734158,0.0003084769,0.0003746895,0.0002360728,0.0005505476,0.000531834],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004004101,"about_ca_system_score_gemma":0.0002153741,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006213215,"about_ca_topic_score_gemma":0.0008610557,"domain_scores_codex":[0.9999063,0.000008392119,0.000005265123,0.00004288485,0.00001735125,0.00001980249],"domain_scores_gemma":[0.9998578,0.00003676783,0.00003403,0.00001765352,0.00002992729,0.00002375735],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001232819,0.000003707371,0.0001646004,0.000008968736,7.167721e-7,0.0000178325,0.00001775448,0.00004831421,0.9989499,0.00009080573,0.00001497448,0.000670005],"study_design_scores_gemma":[0.000007983614,0.0001870229,0.00977391,0.00000990793,0.00000710521,0.0002311604,0.0001167675,0.01064934,0.9764268,0.0004161723,0.002164607,0.0000092301],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8989563,0.0006800921,0.09656691,0.0002254181,0.00004482185,0.00008079058,0.000458507,0.0006877863,0.002299434],"genre_scores_gemma":[0.9189627,0.0004973813,0.07545312,0.0001197433,0.00002961505,0.0002425363,0.0005080613,0.0001175846,0.004069296],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001306421,"threshold_uncertainty_score":0.004370391,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03889887934601346,"score_gpt":0.3107108895230682,"score_spread":0.2718120101770548,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}