{"id":"W2796409097","doi":"10.1111/febs.14454","title":"Understanding lymphocyte metabolism for use in cancer immunotherapy","year":2018,"lang":"en","type":"review","venue":"FEBS Journal","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Victoria; BC Cancer Agency","funders":"Canadian Institutes of Health Research; Carraresi Foundation; Cure Brain Cancer Foundation; Congressional Black Caucus Foundation","keywords":"Cancer immunotherapy; Biology; Epigenetics; Immunotherapy; Cell cycle; Cancer cell; Cell biology; Cancer; T cell; Lymphocyte; Cytotoxic T cell; Computational biology; Cancer research; Immunology; Immune system; Biochemistry; In vitro; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003968405,0.0006335769,0.0008121302,0.001385112,0.000299047,0.001083881,0.0006652669,0.001542818,0.00422195],"category_scores_gemma":[0.0003678954,0.0002262347,0.0004782382,0.0009075089,0.0005648712,0.001504338,0.0007946849,0.001886739,0.003014041],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007365128,"about_ca_system_score_gemma":0.0007531439,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005666359,"about_ca_topic_score_gemma":0.0008059768,"domain_scores_codex":[0.9998604,0.00002726837,0.00001340509,0.00002528901,0.00005504045,0.00001856626],"domain_scores_gemma":[0.9999043,0.00003340595,0.00001543901,0.000006089236,0.00002664104,0.00001406075],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001084713,0.00006296815,0.0002660348,0.01197742,0.00005612988,0.0003950547,0.0001250872,0.0004645839,0.02413398,0.01803191,0.03041283,0.9139656],"study_design_scores_gemma":[0.000007721934,0.00007458508,0.0004279203,0.0009027619,0.00003114398,0.001049773,0.00004244521,0.0001145148,0.003153632,0.004122047,0.9900615,0.00001196651],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0003403342,0.9946679,0.0008221978,0.0006944807,0.0005395034,0.000009832064,0.0000264085,0.00001768427,0.002881659],"genre_scores_gemma":[0.004101766,0.9903768,0.001014368,0.0005849071,0.000545961,0.00002397342,0.00006053058,0.000005939274,0.003285761],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.00422195,"threshold_uncertainty_score":0.0141238,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2131770748315907,"score_gpt":0.3638429557490963,"score_spread":0.1506658809175056,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}