{"id":"W2796484035","doi":"10.1128/iai.00285-18","title":"A Novel Sialylation Site on Neisseria gonorrhoeae Lipooligosaccharide Links Heptose II Lactose Expression with Pathogenicity","year":2018,"lang":"en","type":"article","venue":"Infection and Immunity","topic":"Bacterial Infections and Vaccines","field":"Immunology and Microbiology","cited_by":41,"is_retracted":false,"has_abstract":true,"ca_institutions":"National Research Council Canada","funders":"National Institute of Allergy and Infectious Diseases; National Institute of General Medical Sciences; National Institutes of Health","keywords":"Microbiology; Sialic acid; Neuraminidase; Epitope; Neisseria gonorrhoeae; Lactose; Biology; Heptose; Virulence factor; N-Acetylneuraminic acid; Virulence; Mucin; Mutant; Biochemistry; Antibody; Immunology; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002149326,0.0002202724,0.0002189198,0.0001536329,0.001187132,0.00005243966,0.00006034204,0.0004081862,0.0006715453],"category_scores_gemma":[0.0000751518,0.0001717809,0.00005889123,0.0002196925,0.0001359577,0.000291526,0.0001055525,0.0005482314,0.0001865726],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003630957,"about_ca_system_score_gemma":0.00003337878,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002374069,"about_ca_topic_score_gemma":0.0008276458,"domain_scores_codex":[0.999089,0.0001605568,0.0002380813,0.0002666481,0.00001139997,0.000234341],"domain_scores_gemma":[0.9992567,0.00006293406,0.0001547649,0.0003189986,0.0001691028,0.00003745414],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006483294,0.0003684189,0.01561298,0.000009238158,0.00004629432,6.153835e-8,0.0004541455,0.000003814748,0.9770174,0.00009460174,0.000172765,0.00557196],"study_design_scores_gemma":[0.002586247,0.003297963,0.4170555,0.0001207704,0.0000626634,0.0001465079,0.0000783478,0.00002839565,0.5318469,0.00004290846,0.04435889,0.0003748704],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.996637,0.00006696159,0.0008582177,0.0000752299,0.001017738,0.0002319919,0.00003254355,0.0001652639,0.0009149809],"genre_scores_gemma":[0.9989253,0.00009784875,0.00005274837,0.0001315828,0.0001874465,0.00002382917,0.000127589,0.00001800677,0.0004356669],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4451704,"threshold_uncertainty_score":0.9130581,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01492038998072787,"score_gpt":0.2456754268472127,"score_spread":0.2307550368664849,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}