{"id":"W2796484035","doi":"10.1128/iai.00285-18","title":"A Novel Sialylation Site on Neisseria gonorrhoeae Lipooligosaccharide Links Heptose II Lactose Expression with Pathogenicity","year":2018,"lang":"en","type":"article","venue":"Infection and Immunity","topic":"Bacterial Infections and Vaccines","field":"Immunology and Microbiology","cited_by":41,"is_retracted":false,"has_abstract":true,"ca_institutions":"National Research Council Canada","funders":"National Institute of Allergy and Infectious Diseases; National Institute of General Medical Sciences; National Institutes of Health","keywords":"Microbiology; Sialic acid; Neuraminidase; Epitope; Neisseria gonorrhoeae; Lactose; Biology; Heptose; Virulence factor; N-Acetylneuraminic acid; Virulence; Mucin; Mutant; Biochemistry; Antibody; Immunology; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005612574,0.0002929273,0.0001487532,0.00008029983,0.000129593,0.000301486,0.0001566377,0.0002610604,0.0009834649],"category_scores_gemma":[0.0001070048,0.0001364978,0.0002600208,0.00008622434,0.0002355797,0.0002137428,0.0003021735,0.0003640049,0.0003754646],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002921158,"about_ca_system_score_gemma":0.0001859952,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007397178,"about_ca_topic_score_gemma":0.00105224,"domain_scores_codex":[0.9999529,0.000006990184,0.000003163,0.000009365576,0.00001095979,0.0000164891],"domain_scores_gemma":[0.9999413,0.000007260722,0.00001472122,0.000009812979,0.000007587599,0.0000192912],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006427628,0.000006365281,0.0003328549,0.000009677649,0.000002262518,0.0001032555,0.0000143239,0.00002821875,0.9984877,0.0001769179,0.00001276255,0.0007613183],"study_design_scores_gemma":[0.00001257753,0.0001831752,0.01372732,0.00001118918,0.00001612816,0.0005480635,0.00007078012,0.0008787978,0.9819036,0.0002174817,0.00242204,0.000008916742],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9956553,0.0003249352,0.002738156,0.00005996703,0.00001482815,0.00001224611,0.00009353519,0.00002335527,0.001077593],"genre_scores_gemma":[0.9962204,0.0002382706,0.001971595,0.0000516918,0.000006509927,0.000009919894,0.0002235823,0.00001055907,0.00126754],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009834649,"threshold_uncertainty_score":0.003290057,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01492038998072787,"score_gpt":0.2456754268472127,"score_spread":0.2307550368664849,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}