{"id":"W2796501872","doi":"10.1016/s2213-2600(18)30136-x","title":"Normothermic ex-vivo preservation with the portable Organ Care System Lung device for bilateral lung transplantation (INSPIRE): a randomised, open-label, non-inferiority, phase 3 study","year":2018,"lang":"en","type":"article","venue":"The Lancet Respiratory Medicine","topic":"Transplantation: Methods and Outcomes","field":"Medicine","cited_by":217,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"Bundesministerium für Bildung und Forschung; Deutsche Forschungsgemeinschaft","keywords":"Medicine; Clinical endpoint; Lung transplantation; Lung; Transplantation; Fraction of inspired oxygen; Population; Surgery; Adverse effect; Randomized controlled trial; Internal medicine; Mechanical ventilation","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002541122,0.0003638953,0.0009808855,0.0001096589,0.0006086241,0.00007952826,0.000595529,0.00009662592,0.00007909804],"category_scores_gemma":[0.00007100056,0.0001711119,0.00005180308,0.0004741591,0.0002388444,0.0003317463,0.00003233145,0.000281617,0.000005169072],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001353062,"about_ca_system_score_gemma":0.0002570065,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004420448,"about_ca_topic_score_gemma":0.001043401,"domain_scores_codex":[0.9974321,0.0004214155,0.0006524543,0.0004668963,0.0005708688,0.0004562883],"domain_scores_gemma":[0.9976645,0.0004987579,0.0003408193,0.0008370407,0.0005216378,0.0001372286],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.2386204,0.001610113,0.4007933,0.01703287,0.002928763,0.0006145607,0.1709886,0.00004925824,0.1326314,0.001055011,0.02085232,0.01282324],"study_design_scores_gemma":[0.7450466,0.02008664,0.1464373,0.005272072,0.01050496,0.0003388106,0.02532911,0.0061137,0.01475172,0.00003205948,0.02489653,0.001190542],"study_design_candidate":"randomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9699553,0.0006925136,0.01373365,0.003111344,0.0003842892,0.009580351,0.00007749745,0.0001457793,0.002319237],"genre_scores_gemma":[0.9922935,0.00004401467,0.0009135577,0.003130431,0.002461968,0.0006828922,0.00008666218,0.00007490562,0.0003120415],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5064261,"threshold_uncertainty_score":0.6977741,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0854111441771132,"score_gpt":0.4122737162880399,"score_spread":0.3268625721109267,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}