{"id":"W2796616654","doi":"10.3390/cancers10040118","title":"Roles of Polyploid/Multinucleated Giant Cancer Cells in Metastasis and Disease Relapse Following Anticancer Treatment","year":2018,"lang":"en","type":"article","venue":"Cancers","topic":"Microtubule and mitosis dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":187,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Giant cell; Polyploid; Multinucleate; Metastasis; Cancer cell; Cancer research; Cancer; Biology; Cell; In vitro; Pathology; Ploidy; Medicine; Cell biology; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00004840597,0.0001417635,0.0001821621,0.00004573176,0.00003772727,0.00000825179,0.00007509886,0.00006148162,0.00002902122],"category_scores_gemma":[0.00002537228,0.0001262242,0.00008268083,0.00008852977,0.0001246702,0.000004401089,0.0000415596,0.00003127204,0.000001278182],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000182828,"about_ca_system_score_gemma":0.0003464906,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001130512,"about_ca_topic_score_gemma":0.002232456,"domain_scores_codex":[0.9992386,0.00002785279,0.0001660873,0.000296474,0.00006364803,0.0002074127],"domain_scores_gemma":[0.9995477,0.000005641217,0.00006266731,0.0002097688,0.00004786514,0.0001263675],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002243302,0.00002693923,0.01028994,0.00002036009,0.000147509,0.000003978999,0.0002670975,0.0002059321,0.9820074,0.0000097219,0.0004474415,0.006349319],"study_design_scores_gemma":[0.001703847,0.0003363908,0.005184388,0.0001070738,0.000180999,5.719342e-7,0.0002437743,0.001321567,0.9717259,0.0000113786,0.01890358,0.0002805528],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9949475,0.004282661,0.0000554679,0.00005515192,0.0002173102,0.0001755225,0.0001408943,0.000005690738,0.0001198142],"genre_scores_gemma":[0.9956369,0.003491858,0.0002420846,0.0001366401,0.0001198049,0.000036838,0.00002122376,0.00002181404,0.0002928562],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01845613,"threshold_uncertainty_score":0.5147275,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008726230686395399,"score_gpt":0.2584939017391047,"score_spread":0.2497676710527094,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}