{"id":"W2796616654","doi":"10.3390/cancers10040118","title":"Roles of Polyploid/Multinucleated Giant Cancer Cells in Metastasis and Disease Relapse Following Anticancer Treatment","year":2018,"lang":"en","type":"article","venue":"Cancers","topic":"Microtubule and mitosis dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":187,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Giant cell; Polyploid; Multinucleate; Metastasis; Cancer cell; Cancer research; Cancer; Biology; Cell; In vitro; Pathology; Ploidy; Medicine; Cell biology; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004395673,0.0001027571,0.0002772736,0.0002972846,0.0002080629,0.0004760306,0.0002486287,0.0005783938,0.000465386],"category_scores_gemma":[0.0007459956,0.0000550003,0.0001504724,0.0001457573,0.0003617754,0.0003341941,0.0002877089,0.0004520223,0.00008970962],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006642434,"about_ca_system_score_gemma":0.0002909098,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006629321,"about_ca_topic_score_gemma":0.001517767,"domain_scores_codex":[0.9998571,0.0000482832,0.00001216349,0.0000235501,0.0000381522,0.00002077453],"domain_scores_gemma":[0.9996542,0.0001562595,0.00008343346,0.00001404306,0.00005555482,0.00003654998],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.002783579,0.0001228595,0.03456163,0.002415115,0.0001638846,0.02447535,0.004043736,0.003251484,0.4386702,0.04896444,0.02627688,0.4142708],"study_design_scores_gemma":[0.0001109792,0.002468864,0.1622536,0.001278326,0.0004516719,0.04786505,0.003772455,0.0142038,0.2784848,0.03019214,0.4587452,0.0001732036],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7273666,0.2146068,0.01210614,0.02694514,0.002090839,0.00008140914,0.000257922,0.0002047928,0.01634034],"genre_scores_gemma":[0.9386182,0.04974651,0.001305815,0.001207178,0.00136853,0.00003472271,0.00006661539,0.00002275783,0.007629662],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006642434,"threshold_uncertainty_score":0.004819512,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008726230686395399,"score_gpt":0.2584939017391047,"score_spread":0.2497676710527094,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}