{"id":"W2797054243","doi":"10.1016/j.taap.2018.04.014","title":"In vitro study of doxorubicin-induced oxidative stress in spermatogonia and immature Sertoli cells","year":2018,"lang":"en","type":"article","venue":"Toxicology and Applied Pharmacology","topic":"Sperm and Testicular Function","field":"Medicine","cited_by":33,"is_retracted":false,"has_abstract":false,"ca_institutions":"Institut National de la Recherche Scientifique","funders":"Canadian Institutes of Health Research; Institut National de Recherche et de Sécurité; Warren H. and Clara Cole Foundation","keywords":"Doxorubicin; Oxidative stress; Cytotoxicity; Glutathione; Reactive oxygen species; Intracellular; Sertoli cell; Cell culture; Biology; Pharmacology; Internal medicine; Chemistry; Endocrinology; Cancer research; Cell biology; In vitro; Biochemistry; Chemotherapy; Medicine; Spermatogenesis; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002358172,0.0002190935,0.0002594722,0.0002008534,0.0002515487,0.0001468079,0.0001531186,0.0001457372,0.001615236],"category_scores_gemma":[0.0001043512,0.0001092251,0.0003299089,0.00023646,0.0001696903,0.0002049234,0.0001408866,0.0004264771,0.0002357689],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000208804,"about_ca_system_score_gemma":0.0002586009,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001690701,"about_ca_topic_score_gemma":0.003005956,"domain_scores_codex":[0.9998748,0.00003196127,0.00001959489,0.00002542487,0.00002466618,0.00002351292],"domain_scores_gemma":[0.9998673,0.00004931726,0.0000181998,0.00001653168,0.00002770003,0.00002098319],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000391233,0.0000883914,0.001338869,0.0001257201,0.00001825689,0.0001784432,0.0001519856,0.000116517,0.9958702,0.0001290334,0.00005383086,0.001537537],"study_design_scores_gemma":[0.00004184516,0.002318801,0.02370621,0.00001492221,0.000109143,0.0003406388,0.0002094646,0.0008907029,0.9691547,0.00006347372,0.003140281,0.00000981669],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9905595,0.004216712,0.002511993,0.00008221679,0.00008093874,0.00004195396,0.0004830196,0.00002061659,0.002003013],"genre_scores_gemma":[0.9942248,0.001532567,0.001116522,0.0000433126,0.00001994586,0.00003194548,0.0005457452,0.000004540418,0.002480686],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001690701,"threshold_uncertainty_score":0.005403459,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01486751091223245,"score_gpt":0.3015013976642726,"score_spread":0.2866338867520402,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}