{"id":"W2797054243","doi":"10.1016/j.taap.2018.04.014","title":"In vitro study of doxorubicin-induced oxidative stress in spermatogonia and immature Sertoli cells","year":2018,"lang":"en","type":"article","venue":"Toxicology and Applied Pharmacology","topic":"Sperm and Testicular Function","field":"Medicine","cited_by":33,"is_retracted":false,"has_abstract":false,"ca_institutions":"Institut National de la Recherche Scientifique","funders":"Canadian Institutes of Health Research; Institut National de Recherche et de Sécurité; Warren H. and Clara Cole Foundation","keywords":"Doxorubicin; Oxidative stress; Cytotoxicity; Glutathione; Reactive oxygen species; Intracellular; Sertoli cell; Cell culture; Biology; Pharmacology; Internal medicine; Chemistry; Endocrinology; Cancer research; Cell biology; In vitro; Biochemistry; Chemotherapy; Medicine; Spermatogenesis; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001544051,0.0001588305,0.000459534,0.0002252022,0.00004048587,0.000002816218,0.00004848363,0.0002273848,0.0002307524],"category_scores_gemma":[0.000009778013,0.0001404213,0.00001357743,0.0002201781,0.0002076465,0.00003710421,0.00006789705,0.0003506904,0.000008743419],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002996238,"about_ca_system_score_gemma":0.00004205278,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000497925,"about_ca_topic_score_gemma":0.0001002783,"domain_scores_codex":[0.9989773,0.0001029037,0.0002754373,0.0003237716,0.00006617446,0.0002544359],"domain_scores_gemma":[0.9995676,0.0001357385,0.00008549054,0.00009645161,0.0000340708,0.00008066678],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003185656,0.001266671,0.006578607,0.00005025008,0.00006463636,0.0001127059,0.002395529,0.000003015928,0.9854541,0.00007440002,0.0001657154,0.0006487005],"study_design_scores_gemma":[0.008080274,0.001196749,0.0642892,0.000009924461,0.0001204943,0.00006634161,0.001513707,0.0002033753,0.9242523,0.00007216211,0.00008739263,0.0001081025],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9975445,0.00007399515,0.000002465481,0.0003065097,0.0003065812,0.0009117058,0.000004904892,0.00001552925,0.0008338176],"genre_scores_gemma":[0.998719,0.00002415091,0.00007241595,0.0009284167,0.0001423705,0.00006109055,0.000005602614,0.00001174364,0.00003517909],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06120183,"threshold_uncertainty_score":0.5726216,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01486751091223245,"score_gpt":0.3015013976642726,"score_spread":0.2866338867520402,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}