{"id":"W2797219284","doi":"10.1093/cvr/cvy089","title":"Increased cardiac fatty acid oxidation in a mouse model with decreased malonyl-CoA sensitivity of CPT1B","year":2018,"lang":"en","type":"article","venue":"Cardiovascular Research","topic":"Cardiovascular Function and Risk Factors","field":"Medicine","cited_by":49,"is_retracted":false,"has_abstract":true,"ca_institutions":"Montreal Heart Institute; Université de Montréal; University of Alberta","funders":"Stichting voor de Technische Wetenschappen; Nederlandse Organisatie voor Wetenschappelijk Onderzoek; Academisch Medisch Centrum; École Polytechnique Fédérale de Lausanne; Icahn School of Medicine at Mount Sinai; Velux Stiftung; Hartstichting; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; National Science Foundation","keywords":"Malonyl-CoA; Internal medicine; Endocrinology; Beta oxidation; Carnitine O-palmitoyltransferase; Chemistry; Fatty acid; Medicine; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.008624624,0.0002865349,0.001172651,0.0008204085,0.0001700998,0.00003623702,0.0001298693,0.0002652658,0.00003499702],"category_scores_gemma":[0.0009571465,0.0002327288,0.001439944,0.001342142,0.0006832662,0.0001717078,0.0001336713,0.0006905555,0.00007115338],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003582882,"about_ca_system_score_gemma":0.0006880622,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002961388,"about_ca_topic_score_gemma":0.0002115187,"domain_scores_codex":[0.9939012,0.001771687,0.0003870247,0.000755973,0.002493757,0.0006903913],"domain_scores_gemma":[0.9959432,0.0001632868,0.0000548503,0.001828178,0.001592227,0.0004181997],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.004584657,0.0008947614,0.2669266,0.0007701159,0.01087094,0.0007389453,0.001135391,0.003057966,0.6723098,0.0001669049,0.0009346522,0.03760931],"study_design_scores_gemma":[0.007008611,0.0005777659,0.1742527,0.0002710327,0.0007890789,0.0001880476,0.0006883685,0.01119033,0.8016461,0.00002281639,0.00287062,0.0004944542],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9732217,0.0009636972,0.02237485,0.00005941117,0.00007595617,0.001295171,0.00003839183,0.00008391017,0.001886916],"genre_scores_gemma":[0.9975853,0.0003184803,0.00130974,0.00003410723,0.0002646903,0.00008079576,0.0001051455,0.00007389041,0.0002278262],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1293363,"threshold_uncertainty_score":0.9490406,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04495536703534538,"score_gpt":0.3090306590812191,"score_spread":0.2640752920458738,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}