{"id":"W2797251728","doi":"10.1039/c8md00076j","title":"Design, synthesis and antimicrobial activity of usnic acid derivatives","year":2018,"lang":"en","type":"article","venue":"MedChemComm","topic":"Lichen and fungal ecology","field":"Agricultural and Biological Sciences","cited_by":67,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute for Biological Sciences","funders":"","keywords":"Usnic acid; Antimicrobial; Antibacterial activity; Trichoderma viride; Microbiology; Antibiotics; Penicillium; Chemistry; Fusarium; Pseudomonas aeruginosa; Antifungal; Biology; Bacteria; Lichen; Food science; Botany","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001793117,0.00007900941,0.0001612523,0.000006686738,0.000100629,0.00001095489,0.000126796,0.00007526044,0.0004027555],"category_scores_gemma":[0.0001223335,0.00002996376,0.00002905941,0.0001165912,0.0002405982,0.00006826754,0.00008361656,0.00005341466,0.00001665375],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000006574861,"about_ca_system_score_gemma":0.000005018126,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005483887,"about_ca_topic_score_gemma":0.00008872615,"domain_scores_codex":[0.9994543,0.0001013678,0.00009002262,0.0001506389,0.0000523909,0.0001512846],"domain_scores_gemma":[0.9994742,0.0003435571,0.00005969498,0.00004000022,0.00003838349,0.00004421988],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003832083,0.00005035212,0.005227985,0.000003944745,0.00001076737,4.409046e-7,0.0001002784,2.594973e-8,0.9605027,0.00002057109,0.00030052,0.03374407],"study_design_scores_gemma":[0.00004474835,0.0001542722,0.1429243,0.000006419274,0.000006990629,0.000002572771,0.0000230875,0.00001869199,0.856155,0.00007883647,0.0005197049,0.00006536429],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.99795,0.00002462245,0.00006517935,0.001039445,0.00005307609,0.00008002864,0.000007851483,0.00002119118,0.0007586212],"genre_scores_gemma":[0.9991081,0.00001830412,0.0005675885,0.0001450027,0.0001088148,0.00000572561,0.000001178754,5.502053e-7,0.00004468143],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1376963,"threshold_uncertainty_score":0.4409891,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03244216829854295,"score_gpt":0.2269920322257071,"score_spread":0.1945498639271642,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}