{"id":"W2797339573","doi":"10.3390/vaccines6020023","title":"“Gnothi Seauton”: Leveraging the Host Response to Improve Influenza Virus Vaccine Efficacy","year":2018,"lang":"en","type":"review","venue":"Vaccines","topic":"Influenza Virus Research Studies","field":"Medicine","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University Medical Centre","funders":"Canadian Institutes of Health Research","keywords":"Host (biology); Vaccination; Identification (biology); Virology; Virus; Biology; Vaccine efficacy; Immunology; Influenza vaccine; Host response; Immune system; Computational biology; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaresearch","metaepi_narrow","insufficient_payload"],"consensus_categories":["metaepi_narrow"],"category_scores_codex":[0.00279264,0.001277758,0.003348685,0.001034914,0.000710362,0.0002106803,0.001176931,0.0004960772,0.0003960035],"category_scores_gemma":[0.01142092,0.0007206774,0.0009875702,0.001862781,0.00009369939,0.0001577026,0.001392517,0.001487494,0.004831363],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000625268,"about_ca_system_score_gemma":0.001179129,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001979247,"about_ca_topic_score_gemma":0.0000368683,"domain_scores_codex":[0.9937695,0.0008640833,0.001534626,0.001355473,0.001060085,0.001416245],"domain_scores_gemma":[0.9924293,0.002890241,0.0006598323,0.002610085,0.0008766155,0.0005338994],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00849159,0.0003987758,0.0001660674,0.02010829,0.003183165,0.0003463067,0.002145062,0.000002473855,0.0009033213,0.00002459529,0.1081404,0.8560899],"study_design_scores_gemma":[0.002113962,0.0007569108,0.002642785,0.01076128,0.001396564,0.0001180403,0.00005505119,0.000004254359,0.0001406236,0.000004237254,0.9812952,0.000711097],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.003102726,0.9879031,0.000009946399,0.001710938,0.000839998,0.005354149,0.0001923922,0.0003382663,0.0005485197],"genre_scores_gemma":[0.00003533875,0.9864898,0.0002369456,0.004252453,0.0028315,0.0007995929,0.00003090331,0.0003000613,0.005023377],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.8731548,"threshold_uncertainty_score":0.9999974,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1330090379500457,"score_gpt":0.4383204254434088,"score_spread":0.3053113874933632,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}