{"id":"W2797346936","doi":"10.1080/09687688.2018.1448123","title":"Structural biology of solute carrier (SLC) membrane transport proteins","year":2017,"lang":"en","type":"article","venue":"Molecular Membrane Biology","topic":"Drug Transport and Resistance Mechanisms","field":"Medicine","cited_by":179,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Antiporters; Major facilitator superfamily; Transporter; Solute carrier family; Symporter; Lactose permease; Membrane transport protein; Transport protein; SUPERFAMILY; Membrane transport; Biochemistry; Sequence homology; Homology modeling; Chemistry; Biology; Biophysics; Amino acid; Membrane protein; Membrane; Peptide sequence; Enzyme; Receptor; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001586309,0.0003018277,0.0003676458,0.0002748472,0.0003108276,0.0006407932,0.0002616921,0.000644675,0.0008208499],"category_scores_gemma":[0.0001628631,0.0001074557,0.0003257186,0.0004796014,0.0003041841,0.0005313836,0.0002393573,0.0003548746,0.0005647961],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004481457,"about_ca_system_score_gemma":0.0006416854,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005657287,"about_ca_topic_score_gemma":0.000542924,"domain_scores_codex":[0.9999112,0.00001745847,0.000008064183,0.00001598572,0.00003545829,0.0000118779],"domain_scores_gemma":[0.9999545,0.000007375784,0.0000135388,0.000003292376,0.0000138936,0.000007358992],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001815722,0.00004470452,0.00357096,0.003475266,0.0001344024,0.001597902,0.0004454873,0.003512042,0.8012501,0.01944645,0.007878511,0.1584626],"study_design_scores_gemma":[0.00004635386,0.0004703153,0.01364418,0.0005198969,0.0003048271,0.01078723,0.0006996799,0.01421848,0.3973174,0.0129627,0.5489408,0.00008802526],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.4584943,0.4731205,0.04169897,0.004884867,0.0006070859,0.0001034108,0.001881464,0.0009011514,0.01830835],"genre_scores_gemma":[0.7552227,0.2095743,0.02498344,0.0008457491,0.0002035454,0.00005483233,0.00240945,0.00006290797,0.006643028],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.0008208499,"threshold_uncertainty_score":0.003251612,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01586610227882518,"score_gpt":0.2761757914470758,"score_spread":0.2603096891682506,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}