{"id":"W2797388251","doi":"10.1371/journal.ppat.1006988","title":"Host Pah1p phosphatidate phosphatase limits viral replication by regulating phospholipid synthesis","year":2018,"lang":"en","type":"article","venue":"PLoS Pathogens","topic":"Plant Virus Research Studies","field":"Agricultural and Biological Sciences","cited_by":27,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Institute of General Medical Sciences; Virginia-Maryland College of Veterinary Medicine; China Scholarship Council; U.S. Department of Agriculture; National Science Foundation; National Institutes of Health; University of Alberta","keywords":"Phosphatidate; Biology; Diacylglycerol kinase; Viral replication; Phosphatidic acid; Phosphatidylcholine; Biochemistry; Cell biology; Phospholipid; Genetics; Virus; Membrane; Kinase","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004566461,0.000257027,0.000290321,0.00001587364,0.0007103824,0.0001107162,0.0004539272,0.0001121714,0.0006304165],"category_scores_gemma":[0.00127584,0.0001129174,0.00009781019,0.0004238219,0.0002145383,0.0002295133,0.000184887,0.0001392204,0.0005510712],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000572668,"about_ca_system_score_gemma":0.00001134712,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001830358,"about_ca_topic_score_gemma":0.0001146267,"domain_scores_codex":[0.9976355,0.00013071,0.0003353943,0.0007392227,0.0005075356,0.0006515767],"domain_scores_gemma":[0.9986258,0.0005172423,0.0001793727,0.0002740317,0.0001995337,0.0002040595],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006352027,0.0001372812,0.002129024,0.000008271527,0.00004035602,0.000005318492,0.00007692161,1.062787e-7,0.9404773,0.00005896224,0.01856462,0.03843836],"study_design_scores_gemma":[0.00009541312,0.0002160925,0.01640394,0.00005571775,0.00003232237,0.000003841712,0.00009961418,0.0002439189,0.9520494,0.00006130034,0.03043722,0.0003011758],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9905583,0.0009543208,0.000003224243,0.001147739,0.00008265809,0.0004005377,0.005510878,0.0002078895,0.001134499],"genre_scores_gemma":[0.9971392,0.0005139619,0.0002920271,0.0004059965,0.000478375,0.0001592518,0.000529487,0.000004318313,0.0004773676],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03813718,"threshold_uncertainty_score":0.7083089,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03957445286164092,"score_gpt":0.2569830291723537,"score_spread":0.2174085763107128,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}