{"id":"W2797388251","doi":"10.1371/journal.ppat.1006988","title":"Host Pah1p phosphatidate phosphatase limits viral replication by regulating phospholipid synthesis","year":2018,"lang":"en","type":"article","venue":"PLoS Pathogens","topic":"Plant Virus Research Studies","field":"Agricultural and Biological Sciences","cited_by":27,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Institute of General Medical Sciences; Virginia-Maryland College of Veterinary Medicine; China Scholarship Council; U.S. Department of Agriculture; National Science Foundation; National Institutes of Health; University of Alberta","keywords":"Phosphatidate; Biology; Diacylglycerol kinase; Viral replication; Phosphatidic acid; Phosphatidylcholine; Biochemistry; Cell biology; Phospholipid; Genetics; Virus; Membrane; Kinase","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010565,0.0005240663,0.0002484332,0.0002347324,0.0001871612,0.0005800151,0.0002947367,0.0003217183,0.00149421],"category_scores_gemma":[0.0001389548,0.0001745981,0.0001773541,0.0001322978,0.0002335719,0.0003649156,0.0004344901,0.0005244188,0.0006976307],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003701953,"about_ca_system_score_gemma":0.0002067331,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004493204,"about_ca_topic_score_gemma":0.0005448231,"domain_scores_codex":[0.9998574,0.00001495083,0.0000125858,0.00004715408,0.00003711338,0.00003072081],"domain_scores_gemma":[0.9998714,0.00002580746,0.00003305076,0.00001909261,0.00001642166,0.00003421696],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008379132,0.00001240601,0.0002005397,0.00002914316,0.000002277849,0.00002243719,0.0000059432,0.00008195794,0.9981529,0.000124553,0.00003539702,0.001248644],"study_design_scores_gemma":[0.000009871162,0.00007341815,0.001539885,0.000002529516,0.000007338325,0.0001077964,0.00001071309,0.001658984,0.993867,0.00007395115,0.00264437,0.0000041768],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9863271,0.003479357,0.006215678,0.0001870196,0.00006310685,0.00003177009,0.0007909827,0.0004686867,0.002436332],"genre_scores_gemma":[0.9928095,0.0009537311,0.001969289,0.0000336714,0.00001474883,0.00002568822,0.0007808796,0.00004465972,0.003367852],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00149421,"threshold_uncertainty_score":0.004998565,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03957445286164092,"score_gpt":0.2569830291723537,"score_spread":0.2174085763107128,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}