{"id":"W2797517389","doi":"10.1161/circulationaha.117.033113","title":"Selenoprotein P Promotes the Development of Pulmonary Arterial Hypertension","year":2018,"lang":"en","type":"article","venue":"Circulation","topic":"Pulmonary Hypertension Research and Treatments","field":"Medicine","cited_by":95,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Aging","funders":"","keywords":"Medicine; Hypoxia (environmental); Pulmonary hypertension; Pulmonary artery; Knockout mouse; Right ventricular hypertrophy; Internal medicine; Biomarker; Muscle hypertrophy; Pathology; Endocrinology; Cardiology; Receptor; Chemistry; Oxygen; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001501018,0.0002968074,0.0002386377,0.0003130178,0.0001680362,0.0002974535,0.0001382514,0.0003772552,0.001609889],"category_scores_gemma":[0.0001728708,0.0001451941,0.0003089613,0.0002080608,0.0002875814,0.0001221127,0.0003229469,0.0006159078,0.0003276299],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001455124,"about_ca_system_score_gemma":0.0001609914,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002057848,"about_ca_topic_score_gemma":0.0002739603,"domain_scores_codex":[0.9998869,0.00002111251,0.000009373894,0.00002900541,0.00003140581,0.00002218723],"domain_scores_gemma":[0.9996983,0.00003394425,0.0001177612,0.00002502613,0.00002906492,0.00009595363],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001331826,0.0000972382,0.006360359,0.00007442795,0.00003655468,0.0006822865,0.00002095202,0.00005401457,0.9887892,0.0001053145,0.0002182951,0.002229558],"study_design_scores_gemma":[0.0001660972,0.002553707,0.2379353,0.00003363327,0.0002151894,0.004354456,0.0002039347,0.002558707,0.7433799,0.0005763629,0.008005018,0.00001769561],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9937338,0.001630158,0.002957185,0.0002381285,0.000045002,0.00001777434,0.0003536047,0.0001474799,0.0008768619],"genre_scores_gemma":[0.9967178,0.0007888844,0.0006740563,0.00005007836,0.00001864727,0.00002158643,0.000425677,0.00001307766,0.001290136],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001609889,"threshold_uncertainty_score":0.005385637,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04471316099560056,"score_gpt":0.2836549172204686,"score_spread":0.2389417562248681,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}