{"id":"W2797679714","doi":"10.1016/j.ymthe.2018.04.009","title":"HIV-Specific T Cells Generated from Naive T Cells Suppress HIV In Vitro and Recognize Wide Epitope Breadths","year":2018,"lang":"en","type":"article","venue":"Molecular Therapy","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":20,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"National Institute of Allergy and Infectious Diseases; Simon Fraser University; National Institute on Drug Abuse; National Institute of Neurological Disorders and Stroke; National Institute of Mental Health; National Heart, Lung, and Blood Institute; National Cancer Institute; National Institutes of Health","keywords":"Epitope; Immunology; HIV Antigens; Human leukocyte antigen; Virology; Antigen; Adoptive cell transfer; T cell; Biology; Immune system; Stem cell; Immunity; Medicine; Virus; Viral disease","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003516112,0.0006836851,0.0004516592,0.0003368378,0.0002031391,0.0006439863,0.0003619663,0.0006245045,0.00180874],"category_scores_gemma":[0.0004064671,0.0003074527,0.000322957,0.0001803784,0.0002336114,0.0003826313,0.0004146715,0.002649912,0.0006426904],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001777375,"about_ca_system_score_gemma":0.0002221626,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001403448,"about_ca_topic_score_gemma":0.0002232626,"domain_scores_codex":[0.9996865,0.00006112988,0.00002198454,0.00005193907,0.00006162126,0.0001169152],"domain_scores_gemma":[0.9997652,0.00009764118,0.00002543367,0.00003709471,0.00002198325,0.0000527852],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002230779,0.000169693,0.0004984096,0.00004726711,0.00001378785,0.00009879564,0.0000388915,0.000396874,0.992622,0.0002937081,0.000154574,0.005442868],"study_design_scores_gemma":[0.0002885139,0.002248409,0.004050531,0.00002674032,0.00009082406,0.0012579,0.00009251795,0.003347798,0.9827846,0.0007715151,0.005025655,0.0000150036],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9896809,0.001801729,0.004355491,0.0001269836,0.000136138,0.0001187362,0.0001386411,0.0001288894,0.003512302],"genre_scores_gemma":[0.9947752,0.0007765705,0.001995285,0.0002663433,0.00009966704,0.00006945497,0.0002761862,0.00003328846,0.001707975],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00180874,"threshold_uncertainty_score":0.006050825,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01246611245204484,"score_gpt":0.2322979069536436,"score_spread":0.2198317945015987,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}