{"id":"W2797709183","doi":"10.1002/mds.27360","title":"Disease Modification in Parkinson's Disease: Current Approaches, Challenges, and Future Considerations","year":2018,"lang":"en","type":"review","venue":"Movement Disorders","topic":"Parkinson's Disease Mechanisms and Treatments","field":"Medicine","cited_by":362,"is_retracted":false,"has_abstract":true,"ca_institutions":"Toronto Western Hospital; University of Toronto","funders":"","keywords":"Disease; Parkinson's disease; Dysfunctional family; Neuroscience; Intervention (counseling); Medicine; Bioinformatics; Mechanism (biology); Intensive care medicine; Psychology; Biology; Pathology; Psychiatry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01051904,0.0009576146,0.002029835,0.001671182,0.001038377,0.003896368,0.002112425,0.004818923,0.00429852],"category_scores_gemma":[0.006705638,0.0004018789,0.001244396,0.001415666,0.003285018,0.008124878,0.00246592,0.008394342,0.001673471],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002238504,"about_ca_system_score_gemma":0.006770883,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002014639,"about_ca_topic_score_gemma":0.004622448,"domain_scores_codex":[0.9980966,0.0006811157,0.0002920797,0.0002314623,0.0004967818,0.0002019066],"domain_scores_gemma":[0.9908999,0.005206248,0.0005406011,0.0002589952,0.002359668,0.0007344913],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002333717,0.0002015133,0.0008074944,0.01613471,0.000120965,0.000678651,0.0006758109,0.001030775,0.001666844,0.04863114,0.1162015,0.8136171],"study_design_scores_gemma":[0.00003105576,0.0004196531,0.001152997,0.01380728,0.0001338557,0.001502305,0.001275293,0.0006275948,0.0004291584,0.05082779,0.9297047,0.00008845257],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.000273468,0.958644,0.001060137,0.03639165,0.00226033,0.00001480363,0.00002769142,0.00003546424,0.001292331],"genre_scores_gemma":[0.003059818,0.9763957,0.002717336,0.01228535,0.004520048,0.00005327884,0.00005385169,0.00001523265,0.0008993652],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.01051904,"threshold_uncertainty_score":0.05563068,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1163043361521717,"score_gpt":0.327486974901231,"score_spread":0.2111826387490593,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}