{"id":"W2797791176","doi":"10.1172/jci95305","title":"CNS myeloid cells critically regulate heat hyperalgesia","year":2018,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Neuroinflammation and Neurodegeneration Mechanisms","field":"Neuroscience","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Fraunhofer-Institut für Zelltherapie und Immunologie; Department of Anesthesiology and Critical Care Medicine, Johns Hopkins Medicine; University of Toronto","keywords":"Myeloid cells; Myeloid; Hyperalgesia; Chemistry; Medicine; Neuroscience; Cell biology; Immunology; Biology; Biochemistry; Receptor; Nociception","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001662703,0.0002634402,0.0002727417,0.0001769782,0.0001741841,0.000321178,0.0001356166,0.0002334918,0.001265574],"category_scores_gemma":[0.0001445042,0.0000922885,0.0001556093,0.00008701241,0.0004829064,0.0002506669,0.0003009194,0.0005535674,0.00028864],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000282079,"about_ca_system_score_gemma":0.0002260006,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002131323,"about_ca_topic_score_gemma":0.0003687886,"domain_scores_codex":[0.9998653,0.00002905464,0.00001326737,0.00001876764,0.00002417261,0.00004942559],"domain_scores_gemma":[0.9999086,0.00001050518,0.00003376437,0.000009525077,0.0000121306,0.00002544586],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000418182,0.00002433781,0.0005200786,0.00005688245,0.000002701149,0.0001329253,0.00003751631,0.00003303709,0.9963648,0.0002197043,0.00004006259,0.002149705],"study_design_scores_gemma":[0.0001268814,0.00111149,0.05904636,0.00006967953,0.00007052119,0.001367228,0.0003119182,0.0009222937,0.9307486,0.0007377091,0.005470633,0.00001657296],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9929953,0.004320086,0.0008923156,0.0001232112,0.00002354505,0.00004740928,0.0001398315,0.0000380673,0.001420236],"genre_scores_gemma":[0.9967808,0.001638376,0.0005943285,0.00004135693,0.00002058688,0.00003857015,0.00008825152,0.000008811834,0.000788947],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001265574,"threshold_uncertainty_score":0.004233778,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1152693652201182,"score_gpt":0.3669373391501598,"score_spread":0.2516679739300416,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}