{"id":"W2797879290","doi":"10.1039/c8pp00060c","title":"Photo-induced anticancer activity and singlet oxygen production of prodigiosenes","year":2018,"lang":"en","type":"article","venue":"Photochemical & Photobiological Sciences","topic":"Microbial Metabolism and Applications","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":false,"ca_institutions":"St. Francis Xavier University; Dalhousie University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Nova Scotia Health Research Foundation; Terry Fox Foundation; Beatrice Hunter Cancer Research Institute; Cancer Research Institute","keywords":"Singlet oxygen; Prodigiosin; Cytotoxicity; Chemistry; Photodynamic therapy; Incubation; Estrogen receptor; Molecule; Oxygen; Photochemistry; Conjugated system; Biophysics; Biochemistry; Biology; In vitro; Organic chemistry; Cancer; Escherichia coli","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002981403,0.0001540994,0.00020417,0.00002659997,0.0001801601,0.00002262414,0.0002604345,0.0001376607,0.00005556114],"category_scores_gemma":[0.0002964391,0.0001073485,0.00005812392,0.0002590083,0.001466457,0.00000926508,0.0001710932,0.00007177257,0.000004571719],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000005893824,"about_ca_system_score_gemma":0.00005065759,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007404024,"about_ca_topic_score_gemma":0.00001530302,"domain_scores_codex":[0.9987519,0.00005110194,0.00018799,0.0006272479,0.0001180844,0.0002637155],"domain_scores_gemma":[0.9994529,0.00002176083,0.0001141522,0.0002206685,0.0001059048,0.00008459989],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007049779,0.0001023586,0.0009045521,0.000008080042,0.000008139359,7.985703e-8,0.00001867792,1.534772e-7,0.9973029,0.00007322054,0.0002723103,0.001238996],"study_design_scores_gemma":[0.0001300037,0.000366804,0.005361417,0.00001126427,0.00001002814,0.000009432087,0.00001975455,0.00001320591,0.9893532,0.0003528206,0.004219534,0.0001525525],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9980582,0.0001236066,0.00003842157,0.0001683395,0.0001126192,0.0004917497,0.00001545413,0.00001788855,0.000973742],"genre_scores_gemma":[0.9984502,0.0000978888,0.0008587679,0.0001615485,0.0003043221,0.00007388605,0.000006470557,0.000005388689,0.00004158797],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007949752,"threshold_uncertainty_score":0.5403221,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02943911345485118,"score_gpt":0.3011830423989869,"score_spread":0.2717439289441357,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}