{"id":"W2797879290","doi":"10.1039/c8pp00060c","title":"Photo-induced anticancer activity and singlet oxygen production of prodigiosenes","year":2018,"lang":"en","type":"article","venue":"Photochemical & Photobiological Sciences","topic":"Microbial Metabolism and Applications","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":false,"ca_institutions":"St. Francis Xavier University; Dalhousie University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Nova Scotia Health Research Foundation; Terry Fox Foundation; Beatrice Hunter Cancer Research Institute; Cancer Research Institute","keywords":"Singlet oxygen; Prodigiosin; Cytotoxicity; Chemistry; Photodynamic therapy; Incubation; Estrogen receptor; Molecule; Oxygen; Photochemistry; Conjugated system; Biophysics; Biochemistry; Biology; In vitro; Organic chemistry; Cancer; Escherichia coli","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001161806,0.0002430833,0.0001228285,0.0002031657,0.0000729882,0.0001229902,0.0001313331,0.000178959,0.0009176255],"category_scores_gemma":[0.0001677632,0.00009070287,0.0001704759,0.0001733936,0.0001086617,0.0001776303,0.00009580275,0.0002518174,0.0001081704],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002162628,"about_ca_system_score_gemma":0.000175474,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009733717,"about_ca_topic_score_gemma":0.001029053,"domain_scores_codex":[0.9999324,0.00001008299,0.000004576807,0.00001287415,0.00001538087,0.00002477395],"domain_scores_gemma":[0.9999317,0.00002032244,0.00001386655,0.000009294055,0.00001107604,0.00001373291],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002222169,0.00002156207,0.0001504692,0.00002273145,0.00000370952,0.0000422823,0.00001116574,0.0001403202,0.9981079,0.0001460523,0.00002498672,0.001106573],"study_design_scores_gemma":[0.000006410795,0.000140636,0.0004696401,8.219664e-7,0.000002982619,0.00002327448,0.000003444202,0.0001360561,0.9989401,0.00001336834,0.0002623519,8.973494e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9973637,0.0005956047,0.0007181946,0.00002909849,0.00001078446,0.00001665684,0.0001813171,0.00001841801,0.001066077],"genre_scores_gemma":[0.9982086,0.0002721593,0.0003775718,0.00001172953,0.000002647845,0.000008673474,0.0002014522,0.000005536147,0.0009115792],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009733717,"threshold_uncertainty_score":0.003069699,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02943911345485118,"score_gpt":0.3011830423989869,"score_spread":0.2717439289441357,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}