{"id":"W2798027359","doi":"10.1177/1040638718770239","title":"Immunohistochemical detection of p53, PTEN, Rb, and p16 in canine osteosarcoma using tissue microarray","year":2018,"lang":"en","type":"article","venue":"Journal of Veterinary Diagnostic Investigation","topic":"Veterinary Oncology Research","field":"Medicine","cited_by":23,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"PTEN; Immunohistochemistry; Osteosarcoma; Tissue microarray; Pathology; Microarray; P53 protein; Biology; Cancer research; Medicine; Gene; Gene expression; Signal transduction; PI3K/AKT/mTOR pathway; Cell biology; Genetics","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005054653,0.0002033093,0.0002800374,0.001520263,0.0001782815,0.0002203699,0.0001934449,0.0002428014,0.0007856064],"category_scores_gemma":[0.0004097079,0.0002417407,0.000180818,0.0008038887,0.0001391753,0.0002637081,0.0001850429,0.0001378412,0.0003167119],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001821063,"about_ca_system_score_gemma":0.0001477547,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005973743,"about_ca_topic_score_gemma":0.001429103,"domain_scores_codex":[0.9996297,0.00006277634,0.00006158433,0.00009643204,0.0001051238,0.00004429302],"domain_scores_gemma":[0.9997949,0.00005842985,0.00005117021,0.0000232874,0.00005073753,0.00002143982],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004489274,0.00004774678,0.1207146,0.0001607265,0.00006024768,0.0008747718,0.0001846884,0.0003486348,0.8640913,0.00006220154,0.0001746606,0.01283141],"study_design_scores_gemma":[0.00002281522,0.0008504324,0.7925006,0.00002710951,0.0002026281,0.01257887,0.0004129122,0.005304695,0.1830147,0.0001320346,0.004930614,0.00002260725],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9934196,0.001178624,0.004279689,0.00002343463,0.000006532395,0.00004262697,0.0004661783,0.00004248946,0.0005408465],"genre_scores_gemma":[0.9852647,0.001120429,0.01076112,0.00002615416,0.00001037911,0.0001324235,0.001913109,0.000008955596,0.0007627237],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001520263,"threshold_uncertainty_score":0.002673149,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05063149013376101,"score_gpt":0.3574407586051775,"score_spread":0.3068092684714165,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}