{"id":"W2799040521","doi":"10.1007/978-1-4614-9610-6_387-1","title":"PKR and HIV Replication","year":2015,"lang":"en","type":"article","venue":"","topic":"RNA regulation and disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University; Jewish General Hospital","funders":"","keywords":"Protein kinase R; RNA; Biology; Eukaryotic translation; EIF-2 kinase; eIF2; Replication factor C; Interferon; Transactivation; Protein kinase A; Virology; Cell biology; Translation (biology); Kinase; Eukaryotic DNA replication; Messenger RNA; Mitogen-activated protein kinase kinase; DNA replication; Transcription factor; Ribosome; Cyclin-dependent kinase 2; Genetics; DNA; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005651618,0.0004413514,0.0003349409,0.0005238751,0.0004133593,0.00168277,0.0003899892,0.001019517,0.004122667],"category_scores_gemma":[0.0005537152,0.0002823744,0.0002862956,0.0002470418,0.0006726679,0.001155205,0.0007029353,0.001619082,0.002702921],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00083057,"about_ca_system_score_gemma":0.0004260894,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002759821,"about_ca_topic_score_gemma":0.000183973,"domain_scores_codex":[0.9997771,0.00005454262,0.00002086491,0.00004921738,0.00005644824,0.00004173139],"domain_scores_gemma":[0.9998067,0.00004930246,0.00005578683,0.00002997729,0.00001854221,0.00003970486],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.005845601,0.0006082868,0.003921225,0.001754815,0.0001573384,0.003521066,0.0004336997,0.005660048,0.5239149,0.1006925,0.01657839,0.3369122],"study_design_scores_gemma":[0.0004446251,0.001485178,0.0143986,0.0004018592,0.0001408325,0.01112793,0.0005195914,0.006764327,0.4383082,0.08678032,0.4394743,0.0001541427],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.4433116,0.4217871,0.01222376,0.02901298,0.002650852,0.0001089361,0.001138547,0.001298381,0.08846783],"genre_scores_gemma":[0.8840965,0.07877669,0.004730242,0.001622504,0.001371587,0.00003004904,0.0005605178,0.00005049973,0.02876137],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004122667,"threshold_uncertainty_score":0.01379174,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01767678672299276,"score_gpt":0.2700635679554147,"score_spread":0.2523867812324219,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}