{"id":"W2799379134","doi":"10.1002/mrd.22995","title":"DNA methylation pattern of bovine blastocysts associated with hyperinsulinemia in vitro","year":2018,"lang":"en","type":"article","venue":"Molecular Reproduction and Development","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"Natural Sciences and Engineering Research Council of Canada; Kungl. Skogs- och Lantbruksakademien; Svenska Forskningsrådet Formas","keywords":"Biology; DNA methylation; Epigenetics; Hyperinsulinemia; Epigenome; Differentially methylated regions; Transcriptome; Epigenomics; Insulin; Genomic imprinting; Genetics; Methylation; Gene; Cell biology; Endocrinology; Gene expression; Insulin resistance","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003163062,0.0001069914,0.0001181344,0.00007668533,0.00003925013,0.000008543269,0.00004005751,0.00007608482,0.000005458627],"category_scores_gemma":[0.00009722562,0.00009929294,0.00001501673,0.0001310806,0.00006212046,0.000003619518,0.00004211996,0.00004162936,0.00000155928],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002033725,"about_ca_system_score_gemma":0.00006282388,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001160036,"about_ca_topic_score_gemma":0.00004058512,"domain_scores_codex":[0.9990802,0.00005163011,0.0002370778,0.0003749739,0.0001362208,0.0001198479],"domain_scores_gemma":[0.9994843,0.000003402466,0.0001095741,0.0002083137,0.000157621,0.00003677751],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001313455,0.00005233992,0.003099304,0.000009085059,0.00002856678,0.000001280919,0.0001749842,0.00003494848,0.9541638,0.000001743681,0.000005550417,0.04229701],"study_design_scores_gemma":[0.0005368135,0.0002272395,0.04204872,0.00001524755,0.000005570954,0.000002485697,0.00003327748,0.00003934073,0.9537215,0.00001064466,0.003236179,0.0001229902],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.982338,0.0004435696,0.01673845,0.0000660373,0.00006451222,0.0001591864,0.000001601223,0.000007710528,0.0001809386],"genre_scores_gemma":[0.996929,0.00003205992,0.002721285,0.00003471887,0.00005085123,0.00001378358,0.0001122711,0.00001446022,0.00009150514],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04217402,"threshold_uncertainty_score":0.4049048,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009904782902130127,"score_gpt":0.234147933744973,"score_spread":0.2242431508428429,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}