{"id":"W2799632934","doi":"10.1097/pas.0000000000001084","title":"PD-L1 Immunohistochemistry Assay Concordance in Urothelial Carcinoma of the Bladder and Hypopharyngeal Squamous Cell Carcinoma","year":2018,"lang":"en","type":"article","venue":"The American Journal of Surgical Pathology","topic":"Cancer Immunotherapy and Biomarkers","field":"Medicine","cited_by":103,"is_retracted":false,"has_abstract":true,"ca_institutions":"Health Sciences Centre; Sunnybrook Health Science Centre; University of Toronto","funders":"National Cancer Institute","keywords":"Concordance; Staining; Immunohistochemistry; Medicine; Carcinoma; Antibody; Pathology; Bladder cancer; Tissue microarray; Intraclass correlation; Cancer; Oncology; Internal medicine; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["sts"],"consensus_categories":[],"category_scores_codex":[0.0008222818,0.0001603751,0.0006014365,0.00006726321,0.00007065141,0.000005673929,0.0003003529,0.00006212871,0.00009270597],"category_scores_gemma":[0.00005655408,0.00008774284,0.0002083602,0.0002860993,0.003064109,0.00003129496,0.00007608625,0.0004645141,0.000001804437],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007929834,"about_ca_system_score_gemma":0.0002355125,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001828881,"about_ca_topic_score_gemma":0.000004970653,"domain_scores_codex":[0.9983657,0.0003770078,0.0005901583,0.0001648091,0.0002425976,0.0002596994],"domain_scores_gemma":[0.9984072,0.0003335435,0.0006902197,0.0003383248,0.0001524991,0.00007824732],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0244707,0.000338883,0.1704179,0.00004810622,0.00006683099,0.001386034,0.001917867,0.000001816874,0.7837508,0.00001981622,0.0006507008,0.01693054],"study_design_scores_gemma":[0.009707919,0.005143181,0.892412,0.00006303801,0.0001638116,0.01450727,0.001190645,0.00002963081,0.07377245,0.00009673365,0.002699686,0.0002136399],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9935786,0.002824648,0.00001038774,0.001734428,0.0002495232,0.0001356424,0.000009221932,0.000003286551,0.001454266],"genre_scores_gemma":[0.9986213,0.0001542019,0.00008177581,0.0006065297,0.0003256333,0.000003020376,5.045757e-7,0.00001664799,0.0001903228],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7219942,"threshold_uncertainty_score":0.999649,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009376332697949283,"score_gpt":0.2598185263424308,"score_spread":0.2504421936444815,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}