{"id":"W2799632934","doi":"10.1097/pas.0000000000001084","title":"PD-L1 Immunohistochemistry Assay Concordance in Urothelial Carcinoma of the Bladder and Hypopharyngeal Squamous Cell Carcinoma","year":2018,"lang":"en","type":"article","venue":"The American Journal of Surgical Pathology","topic":"Cancer Immunotherapy and Biomarkers","field":"Medicine","cited_by":103,"is_retracted":false,"has_abstract":true,"ca_institutions":"Health Sciences Centre; Sunnybrook Health Science Centre; University of Toronto","funders":"National Cancer Institute","keywords":"Concordance; Staining; Immunohistochemistry; Medicine; Carcinoma; Antibody; Pathology; Bladder cancer; Tissue microarray; Intraclass correlation; Cancer; Oncology; Internal medicine; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01808228,0.0004054675,0.0007742963,0.003746027,0.0004882879,0.001330568,0.001014351,0.0008961752,0.0009324672],"category_scores_gemma":[0.02431393,0.0006503354,0.0005972841,0.001592491,0.001056056,0.0005770164,0.001167328,0.0005105858,0.0004923876],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007195779,"about_ca_system_score_gemma":0.0004467301,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002181675,"about_ca_topic_score_gemma":0.0035976,"domain_scores_codex":[0.9806265,0.006750302,0.003569972,0.003628024,0.004562124,0.0008629931],"domain_scores_gemma":[0.9767135,0.01235109,0.002654188,0.003621654,0.004226932,0.0004326817],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001012421,0.00005699592,0.921764,0.0002957328,0.0003459977,0.0006321511,0.001220913,0.0008989255,0.05023935,0.0003323171,0.000333378,0.02286781],"study_design_scores_gemma":[0.00002484666,0.0003454273,0.955057,0.00005787047,0.0002449555,0.003084043,0.0004804089,0.005296597,0.03315897,0.000287829,0.001924351,0.00003761199],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9874747,0.002283152,0.00702533,0.0000488937,0.00004446187,0.00007508744,0.0002516286,0.00009597566,0.002700691],"genre_scores_gemma":[0.995109,0.0002622268,0.003805308,0.00002880331,0.00001196958,0.00005999485,0.0003657008,0.00002503733,0.0003319428],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01808228,"threshold_uncertainty_score":0.09562933,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009376332697949283,"score_gpt":0.2598185263424308,"score_spread":0.2504421936444815,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}