{"id":"W2799641062","doi":"10.1002/ajh.25134","title":"Patient‐reported health‐related quality of life from the phase III TOURMALINE‐MM1 study of ixazomib‐lenalidomide‐dexamethasone versus placebo‐lenalidomide‐dexamethasone in relapsed/refractory multiple myeloma","year":2018,"lang":"en","type":"article","venue":"American Journal of Hematology","topic":"Multiple Myeloma Research and Treatments","field":"Medicine","cited_by":49,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; University of Calgary","funders":"Museums Association","keywords":"Placebo; Lenalidomide; Medicine; Clinical endpoint; Internal medicine; Multiple myeloma; Ixazomib; Quality of life (healthcare); Hazard ratio; Dexamethasone; Surgery; Gastroenterology; Randomized controlled trial; Confidence interval; Carfilzomib; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00191638,0.0009682254,0.001505485,0.0003103128,0.0003176723,0.0005623536,0.0004568441,0.0007697531,0.003096096],"category_scores_gemma":[0.0009112057,0.0003720024,0.001527527,0.0003942429,0.0004242083,0.0002538046,0.0003114547,0.001915939,0.0002451352],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000568742,"about_ca_system_score_gemma":0.0006929434,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001363737,"about_ca_topic_score_gemma":0.003828143,"domain_scores_codex":[0.9993891,0.0003789031,0.00002260751,0.0000556337,0.00008110706,0.00007259034],"domain_scores_gemma":[0.9992995,0.0001777127,0.0001708825,0.00002972138,0.00005881035,0.0002633014],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.923353,0.00809883,0.009261569,0.001508983,0.003952801,0.00007615325,0.0001507528,0.001194599,0.01053843,0.0001288666,0.003618314,0.03811768],"study_design_scores_gemma":[0.7337238,0.1681444,0.08722184,0.0001262731,0.003280212,0.0001407884,0.00005968892,0.001125023,0.002236864,0.0001375942,0.003758876,0.00004466143],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9819693,0.007934093,0.0004172885,0.0007072208,0.0001631464,0.001849538,0.004664949,0.00004428746,0.002250142],"genre_scores_gemma":[0.9846193,0.003340293,0.0009554065,0.0008592617,0.0002147347,0.002447321,0.005143887,0.00001735392,0.002402462],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003096096,"threshold_uncertainty_score":0.0103575,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06886877488201884,"score_gpt":0.3831735620730968,"score_spread":0.3143047871910779,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}