{"id":"W2799823436","doi":"10.1167/iovs.17-23283","title":"Conditional Deletion of AP-2α and AP-2β in the Developing Murine Retina Leads to Altered Amacrine Cell Mosaics and Disrupted Visual Function","year":2018,"lang":"en","type":"article","venue":"Investigative Ophthalmology & Visual Science","topic":"Retinal Development and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"National Institute of Dental and Craniofacial Research; National Eye Institute","keywords":"Retina; Amacrine cell; Biology; Retinal; Photoreceptor cell; Neuroscience; Cell biology; Population; Mutant; Inner plexiform layer; Genetics; Gene; Biochemistry; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001948083,0.0009488459,0.0002847589,0.0005986271,0.0001827081,0.000418757,0.0004147111,0.000489837,0.001384166],"category_scores_gemma":[0.0001924511,0.0004497066,0.0002781026,0.0001623474,0.0004415485,0.0002626084,0.0004197021,0.000912136,0.0006502099],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002415614,"about_ca_system_score_gemma":0.0002410622,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005421369,"about_ca_topic_score_gemma":0.0005286018,"domain_scores_codex":[0.999673,0.00002736842,0.00004742922,0.00008680952,0.0001197601,0.00004564831],"domain_scores_gemma":[0.9995298,0.00003298275,0.0002371874,0.00003682349,0.00003211655,0.0001309139],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002924013,0.000007358021,0.0001640688,0.0000145864,0.000003712991,0.00006896153,0.000006063532,0.00003338277,0.999342,0.00005409941,0.000007161476,0.0002693788],"study_design_scores_gemma":[0.00003270682,0.00018605,0.01025386,0.00002056235,0.00003976695,0.001479446,0.00004145352,0.001023023,0.9852063,0.0001158369,0.001593595,0.000007411813],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9908824,0.001269194,0.00626647,0.00007050908,0.00002774521,0.00002717434,0.0004193121,0.0001662484,0.0008710629],"genre_scores_gemma":[0.9920051,0.0007437202,0.003953368,0.00004403876,0.00001184467,0.00005147838,0.0003589194,0.00007167432,0.002759859],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001384166,"threshold_uncertainty_score":0.004630506,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02120086965853671,"score_gpt":0.3164974061560381,"score_spread":0.2952965364975014,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}