{"id":"W2799832501","doi":"10.1039/c8ra00646f","title":"ACI/EG eutectic mixture mediated synthesis, characterization and<i>in vitro</i>osteoblast differentiation assessment of spiropyrrolo[1,2-<i>b</i>]isoquinoline analogues","year":2018,"lang":"en","type":"article","venue":"RSC Advances","topic":"Synthesis and Characterization of Pyrroles","field":"Chemistry","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Winnipeg","funders":"King Saud University","keywords":"Isoquinoline; In vitro; Characterization (materials science); Eutectic system; Chemistry; Osteoblast; Stereochemistry; Biochemistry; Materials science; Organic chemistry; Nanotechnology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001340593,0.0002546345,0.0004284607,0.0001317162,0.00009356545,0.00004112087,0.0001782866,0.0001597907,0.0004842982],"category_scores_gemma":[0.0001889751,0.0002296325,0.00006074046,0.0002298599,0.0001599957,0.0004039755,0.00005786972,0.0001298453,0.000007522501],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004299744,"about_ca_system_score_gemma":0.00003009454,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000004483982,"about_ca_topic_score_gemma":0.00003405277,"domain_scores_codex":[0.9984387,0.00006440865,0.0005435233,0.0003981621,0.0002942586,0.0002609282],"domain_scores_gemma":[0.9988402,0.0002030006,0.0004824702,0.0002573787,0.0001435327,0.00007339118],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001135296,0.0001386727,0.01308067,0.0001780785,0.00002584561,0.000001441456,0.0001103531,0.000002348035,0.9628529,0.00004716035,0.000002586881,0.02344643],"study_design_scores_gemma":[0.0003594693,0.0000414772,0.1403958,0.00022226,0.00004298654,0.000002892571,0.00009982953,0.001937256,0.8542845,0.0000349506,0.002348596,0.0002299277],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9965171,0.0003285508,0.001737918,0.0004095211,0.0001419282,0.0001031974,0.0002351648,0.00007989823,0.0004466762],"genre_scores_gemma":[0.9973114,0.001098908,0.0005500446,0.00007714162,0.0002837008,0.00004553806,0.000536259,0.00003123562,0.00006574859],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1273152,"threshold_uncertainty_score":0.9364141,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007859701307199263,"score_gpt":0.2460190829392307,"score_spread":0.2381593816320314,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}