{"id":"W2799832501","doi":"10.1039/c8ra00646f","title":"ACI/EG eutectic mixture mediated synthesis, characterization and<i>in vitro</i>osteoblast differentiation assessment of spiropyrrolo[1,2-<i>b</i>]isoquinoline analogues","year":2018,"lang":"en","type":"article","venue":"RSC Advances","topic":"Synthesis and Characterization of Pyrroles","field":"Chemistry","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Winnipeg","funders":"King Saud University","keywords":"Isoquinoline; In vitro; Characterization (materials science); Eutectic system; Chemistry; Osteoblast; Stereochemistry; Biochemistry; Materials science; Organic chemistry; Nanotechnology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001758859,0.0002796468,0.0001842295,0.0001358942,0.00007914061,0.000105879,0.000211766,0.000231646,0.0006412581],"category_scores_gemma":[0.0001043923,0.00009218305,0.0001396847,0.0001207242,0.0001370506,0.0001293307,0.0001163773,0.0002510735,0.0002902292],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001635177,"about_ca_system_score_gemma":0.0001377358,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003597843,"about_ca_topic_score_gemma":0.0009683399,"domain_scores_codex":[0.9998858,0.00001396718,0.00001108678,0.00002712821,0.00004187339,0.00002013557],"domain_scores_gemma":[0.9999491,0.000007252467,0.00001634127,0.000005138896,0.00001630791,0.000005896405],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001389573,0.000003508356,0.00002006495,0.00002644858,7.167267e-7,0.00001911651,0.000008800714,0.00004779436,0.9990409,0.00003970262,0.00001361338,0.000765319],"study_design_scores_gemma":[0.00000199419,0.00008050138,0.000223015,0.000001894172,0.000002365282,0.00005053378,0.000005563767,0.0002267038,0.9985576,0.00001078079,0.0008367922,0.000002231141],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9631087,0.002890556,0.02857571,0.00006627856,0.00002529047,0.0001564568,0.000611695,0.0001901636,0.004375207],"genre_scores_gemma":[0.9789863,0.001373532,0.01599542,0.00003930414,0.000003887527,0.00007937414,0.0003792762,0.00002833432,0.003114654],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006412581,"threshold_uncertainty_score":0.002145231,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007859701307199263,"score_gpt":0.2460190829392307,"score_spread":0.2381593816320314,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}