{"id":"W2799837591","doi":"10.1093/jnci/djy067","title":"Molecular Landscape of<i>ERBB2/ERBB3</i>Mutated Colorectal Cancer","year":2018,"lang":"en","type":"article","venue":"JNCI Journal of the National Cancer Institute","topic":"Colorectal Cancer Treatments and Studies","field":"Medicine","cited_by":67,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Cancer Institute; National Institutes of Health; Royal College of Physicians and Surgeons of Canada; University of Texas MD Anderson Cancer Center; Duncan Family Institute for Cancer Prevention and Risk Assessment; American Society of Clinical Oncology","keywords":"KRAS; Neuroblastoma RAS viral oncogene homolog; Colorectal cancer; Medicine; Oncology; Internal medicine; Odds ratio; Microsatellite instability; Confidence interval; ERBB3; Cancer; Cohort; Gene; Genetics; Biology; Epidermal growth factor receptor; Allele; Microsatellite","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004085565,0.000127555,0.0001614436,0.0008123806,0.0002286414,0.0005080706,0.0002197666,0.0002276303,0.001037365],"category_scores_gemma":[0.001099984,0.0001071389,0.0001864441,0.0005991137,0.0002982873,0.0002140777,0.0002592727,0.0002116376,0.000153062],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002822353,"about_ca_system_score_gemma":0.0001698868,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002122762,"about_ca_topic_score_gemma":0.002243913,"domain_scores_codex":[0.9997398,0.000065896,0.00002226933,0.00007138585,0.00004613617,0.00005448652],"domain_scores_gemma":[0.9991059,0.0001509937,0.000517784,0.00003665014,0.00007733142,0.0001114426],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.000191549,0.000008777629,0.9934949,0.00001017537,0.00003105921,0.0002121832,0.00004060833,0.0000833642,0.003527975,0.00003529055,0.00005678118,0.002307373],"study_design_scores_gemma":[0.000002931688,0.00006978966,0.9973142,0.000005369185,0.00003153344,0.001583729,0.0001101129,0.0002136174,0.0004255967,0.00005076086,0.0001898578,0.000002492882],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9991964,0.0003105204,0.00006848376,0.000036434,7.86522e-7,0.000002154171,0.00009258962,0.000003072963,0.0002896105],"genre_scores_gemma":[0.9997467,0.00008593608,0.00004468202,0.00001507324,0.000002755286,0.000001363363,0.00007829109,0.000001403998,0.00002377293],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002122762,"threshold_uncertainty_score":0.004220784,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03031293345121015,"score_gpt":0.3439444175323207,"score_spread":0.3136314840811105,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}