{"id":"W2799973353","doi":"10.1016/j.bbi.2018.04.017","title":"White matter microstructure alterations correlate with terminally differentiated CD8+ effector T cell depletion in the peripheral blood in mania: Combined DTI and immunological investigation in the different phases of bipolar disorder","year":2018,"lang":"en","type":"article","venue":"Brain Behavior and Immunity","topic":"Bipolar Disorder and Treatment","field":"Medicine","cited_by":42,"is_retracted":false,"has_abstract":false,"ca_institutions":"Royal Ottawa Mental Health Centre; University of Ottawa","funders":"Materials Research Institute, Pennsylvania State University; Università degli Studi di Genova","keywords":"CD8; Fractional anisotropy; White matter; T cell; Immunology; Effector; Biology; Chemistry; Pathology; Medicine; Antigen; Immune system; Magnetic resonance imaging","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001822884,0.0002863289,0.0002630253,0.0006034577,0.0002320864,0.0002731771,0.0001188567,0.0002572339,0.0009233267],"category_scores_gemma":[0.0002700324,0.0002676331,0.000132774,0.0002660159,0.0002314374,0.0002143522,0.0001753746,0.0002937218,0.0001096592],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001705055,"about_ca_system_score_gemma":0.0001167469,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001745382,"about_ca_topic_score_gemma":0.002884342,"domain_scores_codex":[0.9999553,0.00001133793,0.000005764054,0.000009580861,0.000006760316,0.00001125319],"domain_scores_gemma":[0.9999,0.00001359154,0.0000333166,0.000007085764,0.00001532282,0.00003062856],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.01420195,0.0005303319,0.3188817,0.0002601804,0.0003266021,0.005029545,0.0005222488,0.0004670213,0.614421,0.0001673591,0.0003798908,0.04481227],"study_design_scores_gemma":[0.00004948965,0.0007329597,0.9883957,0.00001656765,0.0001297855,0.002328595,0.0001845318,0.0004048829,0.00746268,0.0001047848,0.0001832014,0.000006855795],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9986147,0.0006330779,0.0002664491,0.00003025569,0.000005782224,0.00001171169,0.00005560963,0.000007179883,0.0003752313],"genre_scores_gemma":[0.9990233,0.0003396732,0.0002707651,0.00003254824,0.00001119266,0.000008354059,0.00005085149,0.000003086363,0.0002600647],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001745382,"threshold_uncertainty_score":0.00347048,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00932538442031184,"score_gpt":0.2356757082413901,"score_spread":0.2263503238210783,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}