{"id":"W2799996199","doi":"10.1136/jclinpath-2018-205143","title":"Immune checkpoint inhibitor-induced gastrointestinal and hepatic injury: pathologists’ perspective","year":2018,"lang":"en","type":"review","venue":"Journal of Clinical Pathology","topic":"Cancer Immunotherapy and Biomarkers","field":"Medicine","cited_by":138,"is_retracted":false,"has_abstract":true,"ca_institutions":"University Health Network","funders":"","keywords":"Medicine; Ipilimumab; Nivolumab; Pembrolizumab; Immune system; Immunology; Hepatitis; Colitis; Avelumab; Immunotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008227147,0.0004235763,0.0007549173,0.001433517,0.0003136915,0.001070091,0.0005794325,0.001531363,0.002723305],"category_scores_gemma":[0.00151839,0.0002051221,0.0005612163,0.0009749895,0.0006214929,0.00194144,0.0006056579,0.00205804,0.001334857],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004703518,"about_ca_system_score_gemma":0.0007339047,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004768355,"about_ca_topic_score_gemma":0.0009802193,"domain_scores_codex":[0.9996938,0.00007567587,0.00005528703,0.00004256651,0.000101062,0.00003166833],"domain_scores_gemma":[0.9989783,0.0004076027,0.0001502287,0.00003151865,0.0003485237,0.00008387133],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001748724,0.00007406879,0.002194146,0.01211969,0.0001881229,0.007741403,0.0003508726,0.0004282929,0.004352316,0.006537919,0.1707594,0.7950789],"study_design_scores_gemma":[0.00002071292,0.0001344446,0.00255686,0.003276415,0.0001042698,0.03575426,0.0003323994,0.000137974,0.0007625312,0.00357606,0.9533114,0.00003257304],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0009705705,0.9827741,0.0007118325,0.008663109,0.00301587,0.000007626494,0.00003667738,0.00003200373,0.003788218],"genre_scores_gemma":[0.009914598,0.9704321,0.0009903919,0.007124572,0.009463816,0.00001150198,0.00008143212,0.00001033608,0.001971311],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002723305,"threshold_uncertainty_score":0.009110391,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1221296728091969,"score_gpt":0.4593344633350179,"score_spread":0.337204790525821,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}