{"id":"W2800021378","doi":"","title":"DNA methylation in childhood asthma: an epigenome-wide meta-analysis","year":2018,"lang":"en","type":"article","venue":"Utrecht University Repository (Utrecht University)","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université du Québec à Chicoutimi; McGill University","funders":"","keywords":"CpG site; DNA methylation; Epigenome; Asthma; Methylation; Epigenomics; Epigenetics; Medicine; Whole blood; Differentially methylated regions; Immunology; Cord blood; Allergy; Biology; Bioinformatics; Genetics; Gene; Gene expression","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":["metaepi_broad"],"consensus_categories":[],"category_scores_codex":[0.006333887,0.00133829,0.002932256,0.003123916,0.0007231017,0.001248652,0.001210614,0.0009639738,0.001876061],"category_scores_gemma":[0.007032637,0.0008056095,0.01249742,0.005280455,0.0003592092,0.000606948,0.001413382,0.001612703,0.0001796369],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007820856,"about_ca_system_score_gemma":0.0007770816,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0123229,"about_ca_topic_score_gemma":0.01520488,"domain_scores_codex":[0.9955006,0.002350754,0.0002842144,0.001271153,0.0003162909,0.0002769795],"domain_scores_gemma":[0.9959049,0.002242504,0.0004699617,0.0008970621,0.0003029098,0.000182674],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"meta_analysis","study_design_scores_codex":[0.002905871,0.00005575642,0.6375551,0.002017706,0.3255245,0.0004984355,0.0001689745,0.005322743,0.003929123,0.0003341283,0.001680805,0.0200069],"study_design_scores_gemma":[0.0003703227,0.0004678737,0.7209001,0.000501715,0.2613342,0.0006938678,0.0002071588,0.009239778,0.001377166,0.000880559,0.003965746,0.00006139556],"study_design_candidate":"meta_analysis","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8054594,0.1541818,0.02249066,0.001841774,0.0003110831,0.0001557724,0.01374569,0.0004403633,0.001373432],"genre_scores_gemma":[0.9807433,0.01142817,0.004181131,0.0002321243,0.00008705458,0.0001042414,0.002892925,0.00007129636,0.0002597126],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.9970677,"threshold_uncertainty_score":0.03349721,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01918142360390446,"score_gpt":0.2217003350594135,"score_spread":0.2025189114555091,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}