{"id":"W2800174189","doi":"10.1002/jcp.26603","title":"Transglutaminase activity regulates differentiation, migration and fusion of osteoclasts via affecting actin dynamics","year":2018,"lang":"en","type":"article","venue":"Journal of Cellular Physiology","topic":"Blood properties and coagulation","field":"Medicine","cited_by":31,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Institute of Musculoskeletal Health and Arthritis; Canadian Institutes of Health Research","keywords":"Podosome; Osteoclast; Cell biology; Chemistry; Bone resorption; Cellular differentiation; RHOA; Cell fusion; Cell migration; Biochemistry; Cell; In vitro; Cytoskeleton; Biology; Signal transduction","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009895541,0.0002375718,0.0001603666,0.0001435682,0.000108358,0.0002108766,0.0001000133,0.0001562974,0.0004246222],"category_scores_gemma":[0.000056166,0.00008779512,0.0002377885,0.0001177605,0.0001657854,0.0001065152,0.000109269,0.000336586,0.0001258107],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002008249,"about_ca_system_score_gemma":0.0002032358,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001031959,"about_ca_topic_score_gemma":0.001600509,"domain_scores_codex":[0.9999006,0.00001625877,0.000009708939,0.00002298983,0.00002598938,0.00002451104],"domain_scores_gemma":[0.9999536,0.00000546398,0.00001718561,0.000003954176,0.00000762537,0.00001211696],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003854277,0.000007049509,0.00013056,0.00001343482,0.00000162741,0.00001428432,0.000004038167,0.00001110522,0.9992185,0.00001875053,0.0000044473,0.0005376073],"study_design_scores_gemma":[0.0000126007,0.0001902357,0.009166753,0.000003521214,0.00001486797,0.0001486155,0.00002121366,0.0003895845,0.9888333,0.00002093149,0.001195899,0.000002452432],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9916401,0.005063826,0.001959006,0.00004260835,0.00001399786,0.00001841989,0.0001199117,0.00003171582,0.00111044],"genre_scores_gemma":[0.9942616,0.002749521,0.00129312,0.00001897545,0.000005475885,0.00001802625,0.0001806732,0.000005146306,0.001467525],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001031959,"threshold_uncertainty_score":0.00205183,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008585813282858741,"score_gpt":0.2246065027533087,"score_spread":0.21602068947045,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}