{"id":"W2800239232","doi":"10.1039/c8cc03097a","title":"hIAPP forms toxic oligomers in plasma","year":2018,"lang":"en","type":"article","venue":"Chemical Communications","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":38,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Genetics","funders":"National Institute on Aging; Deutsche Forschungsgemeinschaft; Ministerstvo Školství, Mládeže a Tělovýchovy; Seventh Framework Programme; Helmholtz-Gemeinschaft; National Institutes of Health; Deutscher Akademischer Austauschdienst","keywords":"Diabetes mellitus; Chemistry; Toxicity; Plasma glucose; Biophysics; Internal medicine; Medicine; Endocrinology; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001845576,0.000461612,0.0002455333,0.0002980946,0.0002283131,0.0005605577,0.0001644579,0.0006089476,0.001710966],"category_scores_gemma":[0.000253806,0.0002099675,0.0001934456,0.0002228976,0.0002240773,0.0003899088,0.0003722381,0.0006520806,0.001096608],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001683502,"about_ca_system_score_gemma":0.0001376391,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002250017,"about_ca_topic_score_gemma":0.0001414344,"domain_scores_codex":[0.9997863,0.00003763319,0.00001473015,0.00006097912,0.00005668321,0.00004360267],"domain_scores_gemma":[0.9998179,0.00002093738,0.0000737884,0.00002109141,0.00002908101,0.00003720756],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001583013,0.00002999461,0.0008038936,0.00005945087,0.000018568,0.000448818,0.00004870463,0.000033141,0.994792,0.0001639764,0.000197442,0.003245582],"study_design_scores_gemma":[0.00002201798,0.0005204132,0.01168337,0.00003133657,0.00003902592,0.00303565,0.00009603972,0.0004374401,0.9761114,0.000784859,0.007217656,0.00002088776],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9665405,0.01072659,0.01295191,0.00052521,0.0002274785,0.00005916039,0.0005916363,0.0002829326,0.008094585],"genre_scores_gemma":[0.9882139,0.002740342,0.003653287,0.0004657734,0.00007789194,0.00004676823,0.0007171758,0.00002764638,0.004057345],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001710966,"threshold_uncertainty_score":0.005723774,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03717570974491494,"score_gpt":0.3085937254695904,"score_spread":0.2714180157246754,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}