{"id":"W2800423321","doi":"10.1016/j.lfs.2018.04.058","title":"Therapeutic potential of patupilone in epithelial ovarian cancer and future directions","year":2018,"lang":"en","type":"review","venue":"Life Sciences","topic":"Cancer Treatment and Pharmacology","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Department of Medical Biophysics, University of Toronto","keywords":"Epothilones; Ixabepilone; Epothilone; Ovarian cancer; Taxane; In vivo; Cancer research; Cancer; Medicine; Microtubule; Paclitaxel; Pharmacology; Drug; Malignancy; Oncology; Biology; Internal medicine; Chemistry; Breast cancer; Metastatic breast cancer; Cell biology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005079836,0.0006957206,0.001384143,0.001666958,0.000208104,0.001081824,0.000891235,0.0008326689,0.006067049],"category_scores_gemma":[0.000674481,0.0002572513,0.0006328585,0.00144638,0.0004527161,0.001259412,0.0006252388,0.002083463,0.001440849],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003664764,"about_ca_system_score_gemma":0.0009060054,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008485812,"about_ca_topic_score_gemma":0.002178862,"domain_scores_codex":[0.9998887,0.00002037652,0.00002023886,0.00002214123,0.00003296804,0.00001549815],"domain_scores_gemma":[0.9997676,0.0001146427,0.00004291765,0.000007467427,0.00004487807,0.00002247854],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002926803,0.0001492581,0.0002238618,0.01886449,0.0001550746,0.0002850651,0.00005398671,0.0004553153,0.002075987,0.003149281,0.01894287,0.9553522],"study_design_scores_gemma":[0.000162909,0.0003752965,0.00102835,0.004656739,0.0004347536,0.00151061,0.00007922489,0.000211563,0.0009057519,0.002497979,0.988103,0.00003390231],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002140609,0.9983777,0.0001045145,0.0003123045,0.0001455969,0.000005409803,0.00003250748,0.00000721566,0.0008007349],"genre_scores_gemma":[0.001169471,0.9976355,0.0001797258,0.0002823552,0.0001577726,0.000006929393,0.00003672087,0.000001497355,0.0005299899],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.006067049,"threshold_uncertainty_score":0.02029628,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06182321546841823,"score_gpt":0.4048664378634616,"score_spread":0.3430432223950434,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}