{"id":"W2800460894","doi":"10.3389/fcimb.2018.00133","title":"Small Rho GTPases and the Effector VipA Mediate the Invasion of Epithelial Cells by Filamentous Legionella pneumophila","year":2018,"lang":"en","type":"article","venue":"Frontiers in Cellular and Infection Microbiology","topic":"Legionella and Acanthamoeba research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"Toronto Metropolitan University; The Scarborough Hospital; Public Health Ontario; University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Internalization; Cell biology; Legionella pneumophila; Biology; Effector; Secretion; Vacuole; Actin; Cytoskeleton; GTPase; Actin cytoskeleton; Microbiology; Cell; Bacteria; Biochemistry; Cytoplasm","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002143692,0.0003641338,0.0001896894,0.0001536177,0.0001314369,0.0003297413,0.0001820412,0.0003136102,0.0005769603],"category_scores_gemma":[0.0001197992,0.0001402464,0.0003264875,0.0000650665,0.0001911136,0.0002241484,0.0003723591,0.0005725482,0.0002488792],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002277139,"about_ca_system_score_gemma":0.0001916664,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003186803,"about_ca_topic_score_gemma":0.0004293486,"domain_scores_codex":[0.999813,0.00004529051,0.00001202574,0.00002160705,0.00003434164,0.00007370639],"domain_scores_gemma":[0.9999278,0.00001375992,0.0000171813,0.000007168217,0.000007133743,0.00002697317],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001389655,0.0000267728,0.0002453428,0.00003549628,0.000003278087,0.00008787341,0.00001524915,0.0001016976,0.9981171,0.00009900152,0.00003055684,0.001098631],"study_design_scores_gemma":[0.00005210629,0.0008194942,0.02554787,0.00002102541,0.00003241406,0.0005447166,0.0001607997,0.005270711,0.9643896,0.0001609706,0.002988199,0.00001210635],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.993836,0.002095693,0.002040714,0.0001278625,0.00001543894,0.00002631535,0.00009464491,0.00007816352,0.001685185],"genre_scores_gemma":[0.9968867,0.000641037,0.001111179,0.00005094852,0.000006369941,0.00002613711,0.0001214002,0.000006331253,0.00114983],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005769603,"threshold_uncertainty_score":0.001930177,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007248647919494531,"score_gpt":0.2084826777738094,"score_spread":0.2012340298543148,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}