{"id":"W2800460894","doi":"10.3389/fcimb.2018.00133","title":"Small Rho GTPases and the Effector VipA Mediate the Invasion of Epithelial Cells by Filamentous Legionella pneumophila","year":2018,"lang":"en","type":"article","venue":"Frontiers in Cellular and Infection Microbiology","topic":"Legionella and Acanthamoeba research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"Toronto Metropolitan University; The Scarborough Hospital; Public Health Ontario; University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Internalization; Cell biology; Legionella pneumophila; Biology; Effector; Secretion; Vacuole; Actin; Cytoskeleton; GTPase; Actin cytoskeleton; Microbiology; Cell; Bacteria; Biochemistry; Cytoplasm","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005342702,0.0001539284,0.0002214984,0.00006581598,0.0001696002,0.00002068474,0.0001383828,0.0002009339,0.000005809339],"category_scores_gemma":[0.00005310553,0.00009151257,0.00006718404,0.00009987927,0.001362274,0.000004580912,0.0001616346,0.0001597016,0.000004050993],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001128888,"about_ca_system_score_gemma":0.00002947942,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003019333,"about_ca_topic_score_gemma":0.00008403731,"domain_scores_codex":[0.9988145,0.0003674055,0.0002238232,0.0003097,0.00004173246,0.0002428872],"domain_scores_gemma":[0.9995194,0.00006252262,0.0001007338,0.000217777,0.0000561189,0.0000434553],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003072309,0.00004052897,0.005247838,0.00002377367,0.00004356531,0.000001006407,0.0001269602,0.000002320443,0.9810768,0.00001547603,0.0122045,0.0009099793],"study_design_scores_gemma":[0.001778363,0.0004200789,0.0003735496,0.00001152274,0.00002279159,0.00002497804,0.00005046305,0.00008650434,0.9344993,0.0001092978,0.06250402,0.0001191396],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9941358,0.003029895,0.001274533,0.0002792719,0.0007616908,0.0003580708,0.00004199096,0.000004884543,0.0001138762],"genre_scores_gemma":[0.9941406,0.004888552,0.00005856947,0.0002323899,0.0002497361,0.00001938818,0.00009335623,0.00001313296,0.0003043353],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05029952,"threshold_uncertainty_score":0.5019354,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007248647919494531,"score_gpt":0.2084826777738094,"score_spread":0.2012340298543148,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}