{"id":"W2800469711","doi":"10.1128/jcm.00423-18","title":"ThermoMixer-Aided Endpoint Quaking-Induced Conversion (EP-QuIC) Permits Faster Sporadic Creutzfeldt-Jakob Disease (sCJD) Identification than Real-Time Quaking-Induced Conversion (RT-QuIC)","year":2018,"lang":"en","type":"letter","venue":"Journal of Clinical Microbiology","topic":"Prion Diseases and Protein Misfolding","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Manitoba; Public Health Agency of Canada","funders":"","keywords":"Virology; Identification (biology); Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001884884,0.000555292,0.0006089523,0.0002358174,0.0007902097,0.001519861,0.0005913991,0.006925865,0.004010289],"category_scores_gemma":[0.006498833,0.0003228875,0.0004906588,0.0001843376,0.001014946,0.0007129004,0.0004043394,0.009308415,0.003707311],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009172243,"about_ca_system_score_gemma":0.0004096696,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003849347,"about_ca_topic_score_gemma":0.000894559,"domain_scores_codex":[0.9985585,0.0004377212,0.0002334707,0.0001793037,0.0004426706,0.0001484381],"domain_scores_gemma":[0.9963775,0.002460882,0.0002823143,0.0002662617,0.000482873,0.0001301936],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001510113,0.0006072714,0.004773233,0.0005455187,0.00006795966,0.02572701,0.0006760607,0.0006800679,0.1985994,0.01854269,0.5826941,0.1655765],"study_design_scores_gemma":[0.0002502006,0.0008672629,0.003269693,0.0001418365,0.00007665624,0.02102029,0.0002643492,0.004793143,0.102153,0.01098384,0.8560812,0.0000985815],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"commentary","genre_gemma":"empirical","genre_scores_codex":[0.05009424,0.009244121,0.03762537,0.7975622,0.06161475,0.0003704003,0.0005716743,0.002217267,0.04070003],"genre_scores_gemma":[0.3893701,0.008636117,0.07308625,0.4163023,0.02783629,0.0007017252,0.0009596259,0.0006143175,0.08249336],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.006925865,"threshold_uncertainty_score":0.01341575,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04232704465161016,"score_gpt":0.3330578836609825,"score_spread":0.2907308390093724,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}