{"id":"W2800488138","doi":"10.1128/mbio.00390-18","title":"Hacking the Cell: Network Intrusion and Exploitation by Adenovirus E1A","year":2018,"lang":"en","type":"review","venue":"mBio","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":84,"is_retracted":false,"has_abstract":true,"ca_institutions":"Lawson Health Research Institute; Western University","funders":"Canadian Institutes of Health Research; Government of Canada","keywords":"Biology; Computational biology; Proteome; Function (biology); Interaction network; Host (biology); Obligate; Cell biology; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005084104,0.0007026045,0.0009699977,0.001675457,0.0003561395,0.001272831,0.0008745618,0.001134345,0.002494972],"category_scores_gemma":[0.0005187268,0.0003278071,0.0004045363,0.001081285,0.0006411857,0.001571223,0.0007300906,0.001546091,0.002007186],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008528535,"about_ca_system_score_gemma":0.0008206192,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001019407,"about_ca_topic_score_gemma":0.001686984,"domain_scores_codex":[0.9998615,0.00002380979,0.00001881445,0.00002636841,0.00004729451,0.00002223108],"domain_scores_gemma":[0.9998173,0.00007794682,0.00002926012,0.000007862588,0.00004435528,0.00002331473],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001015661,0.00007078265,0.0002347585,0.01151436,0.00008192746,0.0003549761,0.0001092779,0.0003881114,0.003626715,0.01025328,0.02495121,0.948313],"study_design_scores_gemma":[0.00001117361,0.00006824009,0.0003644224,0.001130349,0.00004293227,0.001036345,0.00004924096,0.00006535609,0.001136135,0.001392927,0.9946893,0.00001363927],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002064991,0.9980714,0.0001342121,0.0002234611,0.0001598791,0.000005008402,0.00001284654,0.000009277162,0.00117751],"genre_scores_gemma":[0.001076393,0.9977626,0.0001318341,0.0001611693,0.00007652977,0.000006887371,0.00002202853,0.000001742051,0.0007608306],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002494972,"threshold_uncertainty_score":0.008346498,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03795328527620668,"score_gpt":0.3336587673850044,"score_spread":0.2957054821087978,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}