{"id":"W2800488138","doi":"10.1128/mbio.00390-18","title":"Hacking the Cell: Network Intrusion and Exploitation by Adenovirus E1A","year":2018,"lang":"en","type":"review","venue":"mBio","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":84,"is_retracted":false,"has_abstract":true,"ca_institutions":"Lawson Health Research Institute; Western University","funders":"Canadian Institutes of Health Research; Government of Canada","keywords":"Biology; Computational biology; Proteome; Function (biology); Interaction network; Host (biology); Obligate; Cell biology; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005297046,0.0002715047,0.000358682,0.00003291882,0.0002212031,0.00007858196,0.0003641886,0.0003319984,0.00005143235],"category_scores_gemma":[0.00003360264,0.0001869558,0.0001414799,0.0001436141,0.0001510215,0.000002533326,0.0002645709,0.0002342707,0.00007297255],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002459849,"about_ca_system_score_gemma":0.0001152214,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000009903368,"about_ca_topic_score_gemma":0.00003217417,"domain_scores_codex":[0.9984537,0.0003134101,0.0002625247,0.0004609912,0.0001778429,0.0003315395],"domain_scores_gemma":[0.9991362,0.00004342715,0.0001616072,0.0005309001,0.00005605681,0.00007179838],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001061167,0.00002458569,0.000004693854,0.0009195548,0.00009725186,0.000001750302,0.00003859932,0.000001024204,0.003067751,0.000003856448,0.07936154,0.9163733],"study_design_scores_gemma":[0.0001344909,0.0006397282,6.52854e-7,0.0004467022,0.00007239729,0.000005849374,0.00001048434,0.000003405884,0.003193721,0.00002755246,0.9952455,0.0002195196],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00155422,0.9972143,0.00008316563,0.00003850584,0.0001823335,0.0005057213,0.00002857557,0.00001183142,0.0003813272],"genre_scores_gemma":[0.000245071,0.9968063,0.00006415723,0.0001728127,0.001001658,0.00008607982,0.0003975964,0.00006595776,0.001160391],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9161537,"threshold_uncertainty_score":0.7623837,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03795328527620668,"score_gpt":0.3336587673850044,"score_spread":0.2957054821087978,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}