{"id":"W2800517143","doi":"10.1186/s12985-018-0991-x","title":"HIV-1 tat expression and sulphamethoxazole hydroxylamine mediated oxidative stress alter the disulfide proteome in Jurkat T cells","year":2018,"lang":"en","type":"article","venue":"Virology Journal","topic":"Pneumocystis jirovecii pneumonia detection and treatment","field":"Medicine","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"Robarts Clinical Trials; Western University","funders":"Canadian Institutes of Health Research","keywords":"Jurkat cells; Peroxiredoxin; Western blot; Transfection; Biology; Proteome; Molecular biology; Cell culture; Virology; T cell; Biochemistry; Immunology; Enzyme; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004571888,0.0002101375,0.0003407575,0.0002208048,0.0002289069,0.00003104782,0.0001100622,0.0001417771,0.0002253476],"category_scores_gemma":[0.0001398447,0.0001207843,0.00006131759,0.0001750912,0.0003907281,0.0001151417,0.00008279898,0.0006145873,0.0001030045],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000838497,"about_ca_system_score_gemma":0.00005081001,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001186628,"about_ca_topic_score_gemma":0.00003751278,"domain_scores_codex":[0.9983856,0.000361155,0.0003798832,0.000282118,0.0002257569,0.0003654783],"domain_scores_gemma":[0.9990402,0.0002437701,0.0001995778,0.0002299324,0.00007204094,0.0002144383],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000645309,0.0002366804,0.01286152,0.000009202954,0.00006733903,0.000362667,0.0008108108,0.000007953135,0.9832694,0.000005946888,0.0002938395,0.001429337],"study_design_scores_gemma":[0.006639,0.001931261,0.186974,0.0001551013,0.0001100258,0.002943238,0.0003342955,0.0009190801,0.7965181,0.0003599056,0.002914859,0.0002011723],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9936353,0.0002432258,0.0004785418,0.004608841,0.0002904749,0.0004372905,0.00001937059,0.0000252449,0.000261684],"genre_scores_gemma":[0.9978049,0.0002046003,0.0004773742,0.000726541,0.0003097857,0.00003903601,0.000008679435,0.00002218473,0.00040693],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1867513,"threshold_uncertainty_score":0.4925441,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009175559570355537,"score_gpt":0.2618792284540413,"score_spread":0.2527036688836858,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}