{"id":"W2800631282","doi":"10.1159/000488081","title":"Methylphenidate and Guanfacine Ameliorate ADHD-Like Phenotypes in &lt;b&gt;&lt;i&gt;Fez1&lt;/i&gt;&lt;/b&gt;-Deficient Mice","year":2017,"lang":"en","type":"article","venue":"Complex Psychiatry","topic":"Attention Deficit Hyperactivity Disorder","field":"Medicine","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"National Center for Research Resources; National Institute of Mental Health; National Institutes of Health","keywords":"Methylphenidate; Guanfacine; Nucleus accumbens; Impulsivity; Neurochemical; Dopamine; Atomoxetine; Neuroscience; Attention deficit hyperactivity disorder; Prefrontal cortex; Psychology; Knockout mouse; Phenotype; Pharmacology; Psychiatry; Medicine; Internal medicine; Biology; Gene; Cognition; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001806386,0.0009984561,0.0006047736,0.0008303556,0.0002530914,0.000364005,0.0007315348,0.0009611786,0.00197838],"category_scores_gemma":[0.0001216411,0.0003193198,0.0005938301,0.000212453,0.0005768434,0.0003468842,0.0002999339,0.001539415,0.0004727181],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005161505,"about_ca_system_score_gemma":0.0006144893,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00476623,"about_ca_topic_score_gemma":0.01202332,"domain_scores_codex":[0.9998191,0.00001914276,0.00002287599,0.00004536445,0.00005015558,0.0000434139],"domain_scores_gemma":[0.9997374,0.00001245984,0.0001143817,0.00001560862,0.00001836572,0.0001017551],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007623144,0.0001796506,0.0004045724,0.00006241836,0.00002628988,0.0001518709,0.0000227961,0.00007895636,0.9948512,0.0001416942,0.0002070561,0.003111205],"study_design_scores_gemma":[0.0007915167,0.002612086,0.03020021,0.00009804656,0.00027675,0.001169234,0.0002105475,0.002656571,0.9509364,0.0003548318,0.0106426,0.00005116421],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9883524,0.001556916,0.002993914,0.001007613,0.0001329755,0.00009825817,0.002715875,0.0006587359,0.002483291],"genre_scores_gemma":[0.9758473,0.002871769,0.009677481,0.0005230817,0.00004904112,0.00019729,0.002538647,0.0002727794,0.008022473],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00476623,"threshold_uncertainty_score":0.00947696,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0495366255254938,"score_gpt":0.3273163426634977,"score_spread":0.2777797171380039,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}