{"id":"W2800654890","doi":"10.1016/j.cell.2018.03.073","title":"Interfaces of Malignant and Immunologic Clonal Dynamics in Ovarian Cancer","year":2018,"lang":"en","type":"article","venue":"Cell","topic":"Cancer Immunotherapy and Biomarkers","field":"Medicine","cited_by":385,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Victoria; Genome British Columbia; Canada's Michael Smith Genome Sciences Centre; Vancouver General Hospital; BC Children's Hospital; University of British Columbia","funders":"BC Cancer Foundation; Terry Fox Research Institute; Canada Research Chairs; Michael Smith Health Research BC; Canadian Cancer Society Research Institute; Canadian Institutes of Health Research; Cancer Research Society","keywords":"Biology; Immune system; Ovarian cancer; Cancer immunology; CD8; Tumor microenvironment; Cancer; Cancer research; Immunology; Immunotherapy; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008291226,0.00005431237,0.000119807,0.00004742929,0.00001252887,0.000003229124,0.00003857651,0.00004792113,0.0002803625],"category_scores_gemma":[0.000003363757,0.00004091836,0.0000187306,0.00008329986,0.0001678308,0.00001744561,0.00002125107,0.00005272149,0.000002842492],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007584495,"about_ca_system_score_gemma":0.00004386604,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008832928,"about_ca_topic_score_gemma":0.0005161295,"domain_scores_codex":[0.9996254,0.00001125312,0.0001262655,0.00009731296,0.00004632214,0.00009344162],"domain_scores_gemma":[0.9998151,0.00001155112,0.0000423107,0.00009009206,0.00002580199,0.00001516],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00252189,0.000144391,0.07968886,0.000140527,0.00006676127,0.00001319961,0.0008315565,3.668145e-7,0.8892868,0.00009557445,0.0003371326,0.02687299],"study_design_scores_gemma":[0.004141227,0.001102071,0.3698025,0.0003750237,0.00003954478,0.00002624163,0.001088952,0.0007626213,0.6178434,0.0001233931,0.004534784,0.0001601294],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9921884,0.00313451,0.00001679047,0.0004230176,0.0001550493,0.00009207766,0.000008830781,0.000005443041,0.003975912],"genre_scores_gemma":[0.9978602,0.0009023563,0.0001433549,0.0001382213,0.0000315675,0.00000435286,0.000002662481,0.00000503034,0.000912275],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2901137,"threshold_uncertainty_score":0.3069773,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01368684275218559,"score_gpt":0.2680504945792079,"score_spread":0.2543636518270224,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}