{"id":"W2800654890","doi":"10.1016/j.cell.2018.03.073","title":"Interfaces of Malignant and Immunologic Clonal Dynamics in Ovarian Cancer","year":2018,"lang":"en","type":"article","venue":"Cell","topic":"Cancer Immunotherapy and Biomarkers","field":"Medicine","cited_by":385,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Victoria; Genome British Columbia; Canada's Michael Smith Genome Sciences Centre; Vancouver General Hospital; BC Children's Hospital; University of British Columbia","funders":"BC Cancer Foundation; Terry Fox Research Institute; Canada Research Chairs; Michael Smith Health Research BC; Canadian Cancer Society Research Institute; Canadian Institutes of Health Research; Cancer Research Society","keywords":"Biology; Immune system; Ovarian cancer; Cancer immunology; CD8; Tumor microenvironment; Cancer; Cancer research; Immunology; Immunotherapy; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003922599,0.0001234052,0.0001665779,0.0008572004,0.0004033314,0.001480397,0.0003230531,0.0004779138,0.00298849],"category_scores_gemma":[0.00138428,0.0001548369,0.00009041014,0.0003014133,0.000405695,0.001172987,0.0007321659,0.0004603002,0.00028298],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004878455,"about_ca_system_score_gemma":0.0002362074,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003759649,"about_ca_topic_score_gemma":0.0004415521,"domain_scores_codex":[0.9998025,0.00004707227,0.000008125354,0.00002414575,0.00006612589,0.00005198271],"domain_scores_gemma":[0.9996632,0.0001106178,0.00006013502,0.00002075652,0.00006694786,0.00007824655],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008572015,0.0002096775,0.1042817,0.0004386536,0.00005963928,0.001552373,0.002652131,0.004204447,0.5146536,0.1673065,0.004818759,0.1989654],"study_design_scores_gemma":[0.0001881524,0.001058055,0.4235762,0.000321618,0.0002113042,0.00981455,0.01077302,0.06545573,0.1897144,0.1457026,0.1530762,0.000108095],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9747368,0.007227374,0.004572427,0.001196549,0.00007307238,0.00001747896,0.00006995741,0.00006602144,0.01204037],"genre_scores_gemma":[0.9970977,0.0009162927,0.0005127679,0.0000814977,0.00005801632,0.000007884769,0.00002869147,0.000007892653,0.001289253],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00298849,"threshold_uncertainty_score":0.009997487,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01368684275218559,"score_gpt":0.2680504945792079,"score_spread":0.2543636518270224,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}