{"id":"W2800908142","doi":"10.1194/jlr.r084640","title":"Thematic Review Series: Exosomes and Microvesicles: Lipids as Key Components of their Biogenesis and Functions Extracellular vesicles and their content in bioactive lipid mediators: more than a sack of microRNA","year":2018,"lang":"en","type":"review","venue":"Journal of Lipid Research","topic":"Extracellular vesicles in disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":185,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"Institute of Musculoskeletal Health and Arthritis; Canadian Institutes of Health Research","keywords":"Microvesicles; Cell biology; Lipid signaling; Microvesicle; Biogenesis; Extracellular vesicle; Biology; microRNA; Exosome; Extracellular; Chemistry; Biochemistry; Enzyme","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000452815,0.0009228517,0.001110585,0.003201681,0.0003865011,0.001720351,0.000795105,0.00103426,0.01434188],"category_scores_gemma":[0.001245722,0.0001925553,0.0005727179,0.003188921,0.0004452933,0.001912654,0.0009678888,0.002023348,0.006855355],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006411343,"about_ca_system_score_gemma":0.001456808,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004685679,"about_ca_topic_score_gemma":0.0006557304,"domain_scores_codex":[0.9997367,0.00003508344,0.00004644616,0.00005491474,0.0001015962,0.00002529748],"domain_scores_gemma":[0.9993815,0.0002228247,0.00008581486,0.00002080121,0.0001771803,0.0001118993],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00009774094,0.00008204664,0.0003433899,0.02292774,0.00009175688,0.0002845022,0.0001842441,0.0002850549,0.003412804,0.004517427,0.1887172,0.7790561],"study_design_scores_gemma":[0.000005403439,0.00003173204,0.0004454005,0.002313215,0.00004551179,0.001103677,0.0000525791,0.00004079709,0.0003160349,0.0007974207,0.9948363,0.00001192185],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002916353,0.9874795,0.0003763874,0.001452915,0.005529066,0.00002126765,0.0001078095,0.00003427321,0.004706988],"genre_scores_gemma":[0.001045701,0.9906502,0.000342898,0.0005536614,0.003459735,0.00001751846,0.0001399925,0.000009245244,0.003781004],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.01434188,"threshold_uncertainty_score":0.0479784,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08036341546572788,"score_gpt":0.3471609165695671,"score_spread":0.2667975011038392,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}