{"id":"W2800980126","doi":"10.1093/sleep/zsy061.618","title":"0619 Solriamfetol (JZP-110) for Treatment of Excessive Sleepiness in Narcoleptic Patients With and Without Cataplexy: Results From a Randomized, Phase 3, Clinical Trial","year":2018,"lang":"en","type":"article","venue":"SLEEP","topic":"Sleep and Wakefulness Research","field":"Neuroscience","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Cataplexy; Narcolepsy; Epworth Sleepiness Scale; Placebo; Medicine; Confidence interval; Somnolence; Internal medicine; Excessive daytime sleepiness; Sleep disorder; Modafinil; Anesthesia; Polysomnography; Adverse effect; Insomnia; Psychiatry; Apnea","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007938657,0.0008548066,0.001555633,0.0002710996,0.0002573424,0.000629123,0.0005952453,0.001186668,0.005023013],"category_scores_gemma":[0.0005305052,0.0003617837,0.00120842,0.0002537743,0.0004895404,0.0004249282,0.0002052394,0.001497666,0.001023142],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004210114,"about_ca_system_score_gemma":0.0007654793,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007337427,"about_ca_topic_score_gemma":0.002825009,"domain_scores_codex":[0.9997892,0.00009297646,0.00001934444,0.00003048725,0.0000281523,0.00003996412],"domain_scores_gemma":[0.9997082,0.00006906097,0.00006503152,0.00001526966,0.0000248085,0.0001175712],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.8515819,0.01249735,0.003076675,0.002348746,0.002014628,0.0002895843,0.0001133012,0.000495072,0.02690173,0.0001866614,0.003737579,0.09675676],"study_design_scores_gemma":[0.873924,0.1153818,0.007568914,0.00005425101,0.0003551515,0.0001893012,0.00002858846,0.0003886991,0.0008548982,0.00005244675,0.001182042,0.0000198428],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9899311,0.005246385,0.0002521482,0.0003456972,0.0001617503,0.00109311,0.0007847607,0.0001465468,0.002038387],"genre_scores_gemma":[0.9877996,0.003882585,0.00101361,0.001190558,0.0002113865,0.001537137,0.001826268,0.00002104193,0.002517748],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005023013,"threshold_uncertainty_score":0.01680362,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09194170880758008,"score_gpt":0.4062647689819235,"score_spread":0.3143230601743434,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}