{"id":"W2800980126","doi":"10.1093/sleep/zsy061.618","title":"0619 Solriamfetol (JZP-110) for Treatment of Excessive Sleepiness in Narcoleptic Patients With and Without Cataplexy: Results From a Randomized, Phase 3, Clinical Trial","year":2018,"lang":"en","type":"article","venue":"SLEEP","topic":"Sleep and Wakefulness Research","field":"Neuroscience","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Cataplexy; Narcolepsy; Epworth Sleepiness Scale; Placebo; Medicine; Confidence interval; Somnolence; Internal medicine; Excessive daytime sleepiness; Sleep disorder; Modafinil; Anesthesia; Polysomnography; Adverse effect; Insomnia; Psychiatry; Apnea","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007429272,0.0002807736,0.001118683,0.0001956147,0.0001445531,0.00005647918,0.0002772545,0.0001392703,0.00003503787],"category_scores_gemma":[0.003803054,0.0001878698,0.0001596201,0.0003187807,0.00102528,0.0001988104,0.00007877133,0.00009976407,0.00001283875],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006064619,"about_ca_system_score_gemma":0.0001258605,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004235918,"about_ca_topic_score_gemma":0.0002622214,"domain_scores_codex":[0.9964039,0.0006939582,0.001024413,0.0009014799,0.0004996441,0.0004765494],"domain_scores_gemma":[0.9961231,0.002515045,0.0004234111,0.0005207246,0.0002182406,0.0001994907],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9485425,0.003320784,0.003733155,0.00001423027,0.00007618598,0.000009524883,0.00116703,0.000003714993,0.0003009251,0.00005329371,0.00005144953,0.04272719],"study_design_scores_gemma":[0.9734302,0.00771871,0.0009507915,0.00006964387,0.000137665,8.334024e-7,0.00006265602,0.004433271,0.01212794,0.0003711942,0.0004510023,0.0002460984],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9926528,0.0000411177,0.0008467681,0.0001860644,0.000568382,0.004819527,0.000691617,0.00002733332,0.0001664189],"genre_scores_gemma":[0.9980887,0.00004027592,0.0003723754,0.000074833,0.0004605754,0.0007492681,0.00009438484,0.00003413652,0.0000855052],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04248109,"threshold_uncertainty_score":0.7661108,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09194170880758008,"score_gpt":0.4062647689819235,"score_spread":0.3143230601743434,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}