{"id":"W2801230202","doi":"10.1177/0706743718772514","title":"Can Animal Models Inform on the Relationship between Depression and Alzheimer Disease?","year":2018,"lang":"en","type":"review","venue":"The Canadian Journal of Psychiatry","topic":"Alzheimer's disease research and treatments","field":"Medicine","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"Women and Children’s Health Research Institute; University of Alberta; University of Saskatchewan","funders":"","keywords":"Monoaminergic; Disease; Depression (economics); Animal models of depression; Alzheimer's disease; Neuroscience; Animal studies; Psychology; Animal model; Medicine; Serotonin; Antidepressant; Endocrinology; Internal medicine; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002311395,0.0007576203,0.001861934,0.002131245,0.0002424646,0.001359961,0.001312779,0.001968618,0.004330426],"category_scores_gemma":[0.003789956,0.0003439221,0.0009223322,0.001454791,0.0009248098,0.002549357,0.0006794682,0.002520954,0.001549886],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007481888,"about_ca_system_score_gemma":0.001445845,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002525661,"about_ca_topic_score_gemma":0.00429737,"domain_scores_codex":[0.9994962,0.0002132183,0.00008322892,0.00005478333,0.0001270829,0.00002529846],"domain_scores_gemma":[0.9978661,0.001504344,0.000158703,0.00008774498,0.0003203627,0.00006281595],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001736565,0.0001023174,0.0005064129,0.04663334,0.0002824672,0.0003375052,0.0002099274,0.0002189419,0.001633041,0.01134184,0.04274624,0.8958144],"study_design_scores_gemma":[0.00004594518,0.0001486276,0.00176299,0.02070571,0.0003870166,0.001551591,0.0002378086,0.00008238965,0.0003875329,0.008708031,0.9659512,0.00003129038],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00007014962,0.9981672,0.00008985255,0.0008268819,0.0002473231,0.000005905633,0.00001760138,0.00000395759,0.000571182],"genre_scores_gemma":[0.0006502794,0.9982731,0.0001916683,0.0004745438,0.000146122,0.000009460029,0.00002052906,0.000001207315,0.0002331018],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.004330426,"threshold_uncertainty_score":0.01448673,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1465343688750317,"score_gpt":0.3719738250301259,"score_spread":0.2254394561550943,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}