{"id":"W2801266108","doi":"10.1016/j.tcb.2018.03.003","title":"Cellular Senescence in Postmitotic Cells: Beyond Growth Arrest","year":2018,"lang":"en","type":"review","venue":"Trends in Cell Biology","topic":"Telomeres, Telomerase, and Senescence","field":"Medicine","cited_by":193,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Montréal; Hôpital Maisonneuve-Rosemont","funders":"Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada; Heart and Stroke Foundation of Canada; Fondation de l’Hôpital Maisonneuve-Rosemont; Canadian Diabetes Association","keywords":"Senescence; Biology; Cell biology; Mitosis; Carcinogenesis; Cellular senescence; Apoptosis; Phenotype; Genetics; Cancer","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007880744,0.0009712498,0.001772615,0.002076883,0.0003716996,0.001526193,0.001065976,0.00166492,0.003753377],"category_scores_gemma":[0.0009714831,0.0002425467,0.000427233,0.001866822,0.0008463556,0.002047672,0.001016094,0.002740856,0.002187798],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006231278,"about_ca_system_score_gemma":0.001201775,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006906452,"about_ca_topic_score_gemma":0.001514471,"domain_scores_codex":[0.9997901,0.00003010512,0.00003385355,0.00003933389,0.00008270626,0.0000238717],"domain_scores_gemma":[0.999453,0.0002457525,0.00007936895,0.00001872612,0.0001422365,0.00006088128],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00009095819,0.00005925478,0.0001919745,0.01404423,0.00006441934,0.0002251284,0.00009468388,0.0002441942,0.002668984,0.006202653,0.03586114,0.9402524],"study_design_scores_gemma":[0.00001392837,0.0000652782,0.0005968715,0.002831831,0.0000760738,0.0008680787,0.00007407219,0.00005626834,0.0004895186,0.002920159,0.9919881,0.00001992421],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00006074544,0.9987724,0.00008104889,0.0003600319,0.0002745457,0.000001913339,0.00001088144,0.000005584619,0.0004327838],"genre_scores_gemma":[0.0004111484,0.9986431,0.00007675826,0.0002124244,0.0002935261,0.000003424227,0.00001494136,9.973407e-7,0.0003436196],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003753377,"threshold_uncertainty_score":0.01255625,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04452424926323968,"score_gpt":0.3321859072652557,"score_spread":0.287661658002016,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}