{"id":"W2801292247","doi":"10.2196/resprot.9906","title":"Early Detection of Cardiovascular Changes After Radiotherapy for Breast Cancer: Protocol for a European Multicenter Prospective Cohort Study (MEDIRAD EARLY HEART Study)","year":2018,"lang":"en","type":"article","venue":"JMIR Research Protocols","topic":"Chemotherapy-induced cardiotoxicity and mitigation","field":"Medicine","cited_by":34,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Euratom Research and Training Programme","keywords":"Medicine; Breast cancer; Radiation therapy; Prospective cohort study; Cohort study; Protocol (science); Cohort; Multicenter study; Cancer; Internal medicine; Oncology; Alternative medicine; Pathology; Randomized controlled trial","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.02759826,0.002982938,0.002775713,0.001649154,0.002313449,0.00159016,0.00275222,0.003425912,0.006807893],"category_scores_gemma":[0.01294519,0.001583732,0.003292319,0.003098828,0.001055732,0.001336738,0.002370541,0.001850418,0.002095334],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002026176,"about_ca_system_score_gemma":0.004917153,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003003913,"about_ca_topic_score_gemma":0.005049811,"domain_scores_codex":[0.9825499,0.01202655,0.001918502,0.001678899,0.001071176,0.0007550462],"domain_scores_gemma":[0.9914742,0.00106068,0.001971128,0.002024041,0.002565636,0.0009043531],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"observational","study_design_scores_codex":[0.4787966,0.01636804,0.3087064,0.0127063,0.009082315,0.001105412,0.002644342,0.0108763,0.01290496,0.006991021,0.08161249,0.05820581],"study_design_scores_gemma":[0.1194406,0.03406202,0.7410362,0.002515611,0.004010401,0.000687863,0.001039051,0.007388105,0.003842535,0.002750141,0.0827441,0.0004832867],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"protocol","genre_gemma":"protocol","genre_scores_codex":[0.104293,0.002102011,0.02008443,0.0008679851,0.0006993752,0.813522,0.05302517,0.0004446148,0.004961352],"genre_scores_gemma":[0.04239786,0.0003553618,0.01540722,0.0004601276,0.0001086361,0.921238,0.01885355,0.00004001894,0.001139197],"genre_candidate":"protocol","genre_consensus":"protocol","teacher_disagreement_score":0.02759826,"threshold_uncertainty_score":0.1459553,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1047928841115113,"score_gpt":0.4802436525992496,"score_spread":0.3754507684877383,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}