{"id":"W2801309297","doi":"10.1021/acscatal.8b01224","title":"Cross-Coupling of Phenol Derivatives with Umpolung Aldehydes Catalyzed by Nickel","year":2018,"lang":"en","type":"article","venue":"ACS Catalysis","topic":"Cyclopropane Reaction Mechanisms","field":"Chemistry","cited_by":64,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Centre in Green Chemistry and Catalysis","funders":"Fonds de recherche du Québec – Nature et technologies; China Postdoctoral Science Foundation; Natural Sciences and Engineering Research Council of Canada; Canada Foundation for Innovation; Ministry of Human Resources and Social Security; Canada Research Chairs","keywords":"Umpolung; Nucleophile; Chemistry; Chemoselectivity; Electrophile; Phenol; Catalysis; Organic chemistry; Aldehyde; Ketone; Alkyl; Combinatorial chemistry; Amide","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001487685,0.0005890561,0.0001621163,0.0002502283,0.0001600085,0.0001724212,0.0003291066,0.0002454301,0.0009510063],"category_scores_gemma":[0.000127252,0.0001823682,0.000247178,0.0002072229,0.0001817575,0.0002581858,0.0003546182,0.000386267,0.0004401984],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004812775,"about_ca_system_score_gemma":0.0002464475,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007542759,"about_ca_topic_score_gemma":0.001797798,"domain_scores_codex":[0.9998612,0.00001752457,0.00001026003,0.00003010396,0.00003014768,0.00005067542],"domain_scores_gemma":[0.9999436,0.000006620139,0.00001505725,0.00000872134,0.00001067382,0.00001531294],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005074931,0.00002414033,0.0001236712,0.0001284796,0.00001584175,0.0002548274,0.00006455131,0.0002775564,0.993218,0.0009150784,0.00009067687,0.004836344],"study_design_scores_gemma":[0.000002842603,0.00006977755,0.0002201814,0.000002693274,0.000007107061,0.00009545432,0.000009266774,0.0002895091,0.9967893,0.00004089348,0.002468159,0.000004830841],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.938139,0.004209454,0.04351509,0.0001843921,0.00009581374,0.0001220076,0.0002494121,0.0004413152,0.01304357],"genre_scores_gemma":[0.9856771,0.001552673,0.008411142,0.00003895653,0.00001037866,0.00003064471,0.0001539603,0.00002895954,0.004096291],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009510063,"threshold_uncertainty_score":0.003491938,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009536184950835067,"score_gpt":0.2571594323150027,"score_spread":0.2476232473641676,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}