{"id":"W2801309297","doi":"10.1021/acscatal.8b01224","title":"Cross-Coupling of Phenol Derivatives with Umpolung Aldehydes Catalyzed by Nickel","year":2018,"lang":"en","type":"article","venue":"ACS Catalysis","topic":"Cyclopropane Reaction Mechanisms","field":"Chemistry","cited_by":64,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Centre in Green Chemistry and Catalysis","funders":"Fonds de recherche du Québec – Nature et technologies; China Postdoctoral Science Foundation; Natural Sciences and Engineering Research Council of Canada; Canada Foundation for Innovation; Ministry of Human Resources and Social Security; Canada Research Chairs","keywords":"Umpolung; Nucleophile; Chemistry; Chemoselectivity; Electrophile; Phenol; Catalysis; Organic chemistry; Aldehyde; Ketone; Alkyl; Combinatorial chemistry; Amide","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009358941,0.0002544244,0.0003704683,0.00008952919,0.0001854814,0.00005625394,0.0003635617,0.0001284561,0.0006761633],"category_scores_gemma":[0.0000814937,0.0002251664,0.000102231,0.0004040626,0.0003812307,0.0002857735,0.000116891,0.0001485172,0.00008295839],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009715854,"about_ca_system_score_gemma":0.00006427672,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005173247,"about_ca_topic_score_gemma":0.00007257948,"domain_scores_codex":[0.9984467,0.000004051706,0.0003698561,0.0004742865,0.0003806561,0.0003244526],"domain_scores_gemma":[0.9984257,0.00007804091,0.0003311552,0.0007596922,0.0003089791,0.00009641331],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006865888,0.000075991,0.0048724,0.0001209173,0.0002671915,0.000002807714,0.00119585,0.00001943831,0.9917381,0.00003606508,0.00006163582,0.00154091],"study_design_scores_gemma":[0.0005707497,0.00003023495,0.0001371482,0.00004880079,0.0001751736,0.00001046015,0.001536418,0.0001596951,0.9963527,0.00002914043,0.0006761656,0.0002733593],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9955897,0.0003030701,0.0009358451,0.00002705052,0.00003456965,0.00006800763,0.00005993606,0.0001243087,0.002857502],"genre_scores_gemma":[0.996975,0.00002761527,0.0008592099,0.00001539273,0.0001265147,0.00003067655,0.0004038808,0.00005797719,0.001503743],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004735252,"threshold_uncertainty_score":0.9182019,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009536184950835067,"score_gpt":0.2571594323150027,"score_spread":0.2476232473641676,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}