{"id":"W2801471608","doi":"10.1177/0748233718758233","title":"Nano-CuO impairs spatial cognition associated with inhibiting hippocampal long-term potentiation via affecting glutamatergic neurotransmission in rats","year":2018,"lang":"en","type":"article","venue":"Toxicology and Industrial Health","topic":"Neuroscience and Neuropharmacology Research","field":"Neuroscience","cited_by":40,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan","funders":"National Natural Science Foundation of China","keywords":"Excitatory postsynaptic potential; Long-term potentiation; Morris water navigation task; Hippocampal formation; Neurotoxicity; Neurotransmission; Hippocampus; Chemistry; Glutamate receptor; Postsynaptic potential; Glutamatergic; Neuroscience; Internal medicine; Biophysics; Endocrinology; Medicine; Biology; Toxicity; Inhibitory postsynaptic potential; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001611673,0.0007548281,0.0005925581,0.0005324497,0.0002207221,0.0002649202,0.0003719013,0.0005223483,0.0009230209],"category_scores_gemma":[0.0001847278,0.0003062229,0.0005283479,0.000180473,0.0004627535,0.0004295711,0.0003175866,0.001092277,0.0001576191],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003129235,"about_ca_system_score_gemma":0.0004504441,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002123572,"about_ca_topic_score_gemma":0.00315414,"domain_scores_codex":[0.9998376,0.00001117166,0.00001941953,0.00003599013,0.00004285108,0.00005286974],"domain_scores_gemma":[0.9997866,0.00001123646,0.00007448361,0.00002004764,0.00002843703,0.00007923607],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002377733,0.001619372,0.001303822,0.0001535512,0.00005914136,0.0001821831,0.0001083224,0.0002381852,0.9876416,0.0001457793,0.0001775719,0.005992819],"study_design_scores_gemma":[0.000203338,0.01370445,0.01838608,0.00004096178,0.0001692253,0.0002820256,0.0002642668,0.002303738,0.9622996,0.0004101238,0.001895062,0.0000411172],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9973139,0.0006805977,0.001046179,0.000150742,0.00005536691,0.00002576272,0.0001496654,0.00008869565,0.0004890963],"genre_scores_gemma":[0.9940314,0.001066893,0.001249735,0.0001350113,0.00001888701,0.0001066031,0.0002050248,0.00001783097,0.003168571],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002123572,"threshold_uncertainty_score":0.004222453,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0788201168651774,"score_gpt":0.3540580682938663,"score_spread":0.2752379514286889,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}