{"id":"W2801546201","doi":"10.1017/s0033583518000045","title":"Copper chaperone blocks amyloid formation via ternary complex","year":2018,"lang":"en","type":"article","venue":"Quarterly Reviews of Biophysics","topic":"Trace Elements in Health","field":"Nursing","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Fondation Chalmers; Vetenskapsrådet; Knut och Alice Wallenbergs Stiftelse","keywords":"Chaperone (clinical); Protein folding; Chemistry; Copper; Protein aggregation; Ternary complex; Amyloid (mycology); Biophysics; Cell biology; Biochemistry; Biology; Enzyme","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000220286,0.0002533259,0.0003836351,0.0002336082,0.0002128853,0.0003653122,0.0004605236,0.0002509452,0.001318323],"category_scores_gemma":[0.0003838104,0.0001273997,0.0001682637,0.0002029357,0.0002989153,0.00013631,0.0003314037,0.0004724471,0.0003623884],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003563294,"about_ca_system_score_gemma":0.0003701026,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001001439,"about_ca_topic_score_gemma":0.001334254,"domain_scores_codex":[0.9997439,0.00006311224,0.00002458497,0.00003666512,0.00007606498,0.00005575551],"domain_scores_gemma":[0.9997464,0.00004437058,0.0000655662,0.00003845208,0.00005394522,0.00005130238],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0009089595,0.0003013746,0.0003557648,0.0001208525,0.0000324321,0.0001022345,0.00006714342,0.0001141788,0.9913744,0.000446145,0.0008374834,0.005339084],"study_design_scores_gemma":[0.00008249448,0.0007900927,0.001230211,0.000009564258,0.00002701475,0.0001800636,0.00002089193,0.001097605,0.9923253,0.00008936587,0.004141435,0.000006036366],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9946285,0.001588885,0.001475615,0.000165345,0.000106636,0.00002183792,0.00007227502,0.0001905127,0.001750442],"genre_scores_gemma":[0.9958156,0.0005097002,0.0008768045,0.0000452159,0.00002058579,0.00001546685,0.0001338209,0.00002618908,0.002556817],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001318323,"threshold_uncertainty_score":0.004410267,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04236457772532372,"score_gpt":0.3212903453689356,"score_spread":0.2789257676436119,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}